Beta
ManageSearchChatDiscover
184947

CRECTROPHOTOMETRIC DETERMINATION OF PHENYLBUTAZONE AND OXYPHENBUTAZONE THROUGH CONDENSATION WITH P-DIMETHYLAMINOBENZALDEHYDE

Article

Last updated: 22 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

-

Abstract

P-Dimethylaminobenzaldehyde is used for colorimetric determination of phenylbutazone and oxyphenbutazone both in pure form and in their tablets. The reaction proceeds via first formation of aldol intermediate which suffers aminolysis by piperidine with subsequent elimination to afford intensive and stable colored disubstituted styrene. Beer's law is obeyed in the range of 0.08-0.4 mg mg-1 for phenylbutazone and 0.08-0.24 mg ml for oxyphenbutazone.

DOI

10.21608/zjps.1997.184947

Authors

First Name

Gehard

Last Name

Rücker

MiddleName

-

Affiliation

Pharmacy Institute, Bonn University, Germany

Email

-

City

-

Orcid

-

First Name

Magda

Last Name

Ayad

MiddleName

-

Affiliation

Analytical Chemistry Department, Faculty of Pharmacy, Zagazig University. Zagazig. Egypt.

Email

mmayad@pharmacy.zu.edu.eg

City

-

Orcid

-

First Name

Mohamed

Last Name

El-Sadek

MiddleName

-

Affiliation

Medicinal Chemistry Department, Faculty of Pharmacy, Zagazig University, Egypt

Email

mmel-sadek@pharmacy.zu.edu.eg

City

-

Orcid

-

First Name

Samia

Last Name

Moustafa

MiddleName

-

Affiliation

Medicinal Chemistry Department, Faculty of Pharmacy, Zagazig University, Egypt

Email

smmoustafa@pharmacy.zu.edu.eg

City

-

Orcid

-

Volume

6

Article Issue

2

Related Issue

24768

Issue Date

1997-12-01

Receive Date

1997-10-27

Publish Date

1997-12-01

Page Start

81

Page End

85

Print ISSN

1110-5089

Online ISSN

2356-9786

Article File

ZJPS_Volume 6_Issue 2_Pages 81-85.pdf

PDF . 2.3MB

Link

https://zjps.journals.ekb.eg/article_184947.html

Detail API

https://zjps.journals.ekb.eg/service?article_code=184947

Order

13

Type

Original Article

Type Code

862

Publication Type

Journal

Publication Title

Zagazig Journal of Pharmaceutical Sciences

Publication Link

https://zjps.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023