184796

SYNTHESIS AND CHARACTERIZATION OF SOME PEPTIDES HAVING SURFACE ACTIVITY USING POLYETHYLENE GLYCOL

Article

Last updated: 04 Jan 2025

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Abstract

In order to obtain peptide based amphoteric surfactants with antimicrobial activity, six polyethylene glycol bounded peptide chains were synthesized using the liquid phase method. The investigated chains contain aliphatic and aromatic amino acids in different sequences. Polyethylene glycol monomethyl ether was empolyed as soluble polymeric support; dicyclohexyl carbodiimide was used as the coupling reagent while the acid labile tert. butyloxy carbonyl group was applied in N-protection. The synthesized peptide chains was found to have promising surface properties beside their antimicrobial activity.

DOI

10.21608/zjps.1998.184796

Authors

First Name

Somaya

Last Name

Abdel-Rahman

MiddleName

-

Affiliation

Chemistry Dept., Faculty of Science, Zagazig University, Egypt.

Email

somaya.abdel-rahman@yahoo.com

City

-

Orcid

-

First Name

Abdel-Monem

Last Name

Eissa

MiddleName

-

Affiliation

Chemistry Dept., Faculty of Science, Zagazig University, Egypt.

Email

abdel-monem.eissa@yahoo.com

City

-

Orcid

-

First Name

Nadia

Last Name

Ameen

MiddleName

-

Affiliation

Chemistry Department, Girls College for Education, Jeddah, K.S.A

Email

nadia.ameen@yahoo.com

City

-

Orcid

-

First Name

Ahmed

Last Name

Naglah

MiddleName

-

Affiliation

Chemistry Dept., Faculty of Science, Zagazig University, Egypt.

Email

ahmed.naglah@yahoo.com

City

-

Orcid

-

Volume

7

Article Issue

2

Related Issue

24766

Issue Date

1998-12-01

Receive Date

1998-08-19

Publish Date

1998-12-01

Page Start

27

Page End

32

Print ISSN

1110-5089

Online ISSN

2356-9786

Link

https://zjps.journals.ekb.eg/article_184796.html

Detail API

https://zjps.journals.ekb.eg/service?article_code=184796

Order

4

Type

Original Article

Type Code

862

Publication Type

Journal

Publication Title

Zagazig Journal of Pharmaceutical Sciences

Publication Link

https://zjps.journals.ekb.eg/

MainTitle

SYNTHESIS AND CHARACTERIZATION OF SOME PEPTIDES HAVING SURFACE ACTIVITY USING POLYETHYLENE GLYCOL

Details

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Article

Created At

22 Jan 2023