Chemical study of Echium horridum Batt, and E. rauwolfii Del. reveals isolation of echimidine and different picture of minor lkhcide. Thus, the macro- and micromorphological characters of roots, stems, leaves and flowers of Echium horridum Batt and E. rauwolfii Del. are presented with the aim of finding out the characteristic feature by which the plants could be identified and differentiated from each other in both entire and powdered forms, and from other closely related species.