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181595

MOLLUSCICIDAL STEROIDAL SAPONINS FROM YUCCA ELEPHANTIPES

Article

Last updated: 04 Jan 2025

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Abstract

Three spirostanol and two furostanol saponins have been isolated from the methanol extract of the leaves of Yucca elephantipes .The structures of these saponins were established as 3-O-β -D-xylopyranosyl-(1→2)- B-D- glucopyranosyl-(1→3)- β-D-glucopyranoside D- galactopyranoside yamogenin (I),3-O-β-D-xylopyranosyl-(1-→2)[ -β-D- glucopyranosyl-( 1-3 )] , 26-B-D- glucopyranoside (25 S) -furost- 5-ene-3,22,26 -triol (II), 3- O- α -L -rhamnopyranosyl- ( 1→2 )-[ β- D-xylopyranosyl- (1-→3) -β-D-glucopyranosyl-(1–>4)- β-D-galactopyranoside gitogenin (III), 3-O-β-D-xylopyranosyl- ( 1→ 3)- [β-D-glucopyranosyl -(1→2) - ß-D-glucopyranosyl-(1→4)- β- D-galactopyranoside gitogenin (IV),and 26-0-β-D-glucopyranosyl-22-0-methyl (25R)-5-furostan -2,3,26-tetrol-3-O-[α-L-rhamnopyranosyl -(1->3)]- ß -D-glucopyranosyl -(1->2)- β-D-glucopyranosyl-(1-4)- β-D- galactopyranoside (V). Saponins I, III and IV showed high molluscicidal activities against Biomphalaria alexandrina snails after 24 hours exposure (LC90 = 4,9 and 7 ppm ) whereas saponins II and V were inactive up to 50 ppm

DOI

10.21608/zjps.2001.181595

Authors

First Name

Mortada

Last Name

El-Sayed

MiddleName

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Affiliation

Laboratory of Medicinal Chemistry, Theodor Bilharz Research Institute, Imbaba, Giza, Egypt.

Email

mortada.el-sayed@yahoo.com

City

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Orcid

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First Name

Hanan

Last Name

El-Nahas

MiddleName

-

Affiliation

Department of Medicinal Chemistry Theodor Bilharz Research Institute Warrak El-Hadar, Giza, Egypt.

Email

hanan.el-nahas@yahoo.com

City

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Orcid

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Volume

10

Article Issue

1

Related Issue

24759

Issue Date

2001-06-01

Receive Date

2001-04-12

Publish Date

2001-06-01

Page Start

41

Page End

48

Print ISSN

1110-5089

Online ISSN

2356-9786

Link

https://zjps.journals.ekb.eg/article_181595.html

Detail API

https://zjps.journals.ekb.eg/service?article_code=181595

Order

8

Type

Original Article

Type Code

862

Publication Type

Journal

Publication Title

Zagazig Journal of Pharmaceutical Sciences

Publication Link

https://zjps.journals.ekb.eg/

MainTitle

MOLLUSCICIDAL STEROIDAL SAPONINS FROM YUCCA ELEPHANTIPES

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Article

Created At

22 Jan 2023