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178076

EVALUATION OF GREEN TEA EXTRACT AS A HYPOGLYCEMIC AGENT IN EXPERIMENTALLY DIABETIC RATS

Article

Last updated: 22 Jan 2023

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Abstract

Recently great attention has been forwarded to natural products especially those owing medicinal properties e.g. Korean ginseng roots, Nigella sativa, Curcuma longa and green tea. In our study we select the last product as drinking tea is a traditional dietary habit in Egypt. Green tea, catechin is its active constituent, has received a great attention as a protective agent against cancer and cardiovascular diseases. Data reported regarding the effect of catechin on carbohydrate metabolism are scarce few of them referred to its hypoglycemic effect, but without a definite explanation for the exact mechanism of action. The present work aimed mainly to study some of the metabolic actions of catechin. Metformin (Biguanide) which is a well known hypoglycemic drug has been included for comparison. Administration of both catechin and metformin individually for four and ten weeks respectively to normal and alloxan diabetic rats was done. Parameters studied were blood glucose, lactate, pyrurvate, liver glycogen, insulin, total cholesterol (TG), triacylglycerol (1G), non esterified fatty acids (NEFA) and lipid peroxidation product(MDA).

DOI

10.21608/zjps.2003.178076

Authors

First Name

Mohamed

Last Name

El-Seweidy

MiddleName

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Affiliation

Biochemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.

Email

mmel-seweidy@pharmacy.zu.edu.eg

City

-

Orcid

-

First Name

Fatma

Last Name

Abdallah

MiddleName

-

Affiliation

Department of Biochemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt

Email

frabdallah@pharmacy.zu.edu.eg

City

-

Orcid

-

First Name

Rawia

Last Name

Amin

MiddleName

-

Affiliation

Biochemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.

Email

rsamin@pharmacy.zu.edu.eg

City

-

Orcid

-

First Name

Atef

Last Name

Abdelbaky

MiddleName

-

Affiliation

Biochemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.

Email

atef.abdelbaky@yahoo.com

City

-

Orcid

-

Volume

12

Article Issue

1

Related Issue

24755

Issue Date

2003-06-01

Receive Date

2003-04-24

Publish Date

2003-06-01

Page Start

44

Page End

50

Print ISSN

1110-5089

Online ISSN

2356-9786

Link

https://zjps.journals.ekb.eg/article_178076.html

Detail API

https://zjps.journals.ekb.eg/service?article_code=178076

Order

7

Type

Original Article

Type Code

862

Publication Type

Journal

Publication Title

Zagazig Journal of Pharmaceutical Sciences

Publication Link

https://zjps.journals.ekb.eg/

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Article

Created At

22 Jan 2023