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169384

SYNTHESIS OF SOME MALEIMIDE DERIVATIVES VIA REGIO AND STEREOSELECTIVE REDUCTION USING SODIUM BOROHYDRIDE

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Last updated: 04 Jan 2025

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Abstract

Synthesis of specific maleimide derivatives was performed through the stereospecific use of sodium borohydride. The reduction took place on only one of the carbonyl which is adjacent to the phenylamino group or the alky1 amino group. Our results were confirmed by the presence of the formed hydroxyl group using chromatographic and spectroscopic techniques.

DOI

10.21608/zjps.2007.169384

Authors

First Name

Hanan

Last Name

Abdel-Fattah

MiddleName

-

Affiliation

Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt

Email

haabdel-fattah@pharmacy.zu.edu.eg

City

-

Orcid

-

First Name

Mohamed

Last Name

El-Bermawy

MiddleName

-

Affiliation

Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt

Email

mael-bermawy@pharmacy.zu.edu.eg

City

-

Orcid

-

First Name

Azza

Last Name

Kadry

MiddleName

-

Affiliation

Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt

Email

amkadry@pharmacy.zu.edu.eg

City

-

Orcid

-

First Name

Mohamed

Last Name

Al-Ashmawi

MiddleName

-

Affiliation

Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt

Email

mial-ashmawi@pharmacy.zu.edu.eg

City

-

Orcid

-

First Name

H.D.

Last Name

Martin

MiddleName

-

Affiliation

Institut fur Organic Chemie and Makromolekular Chemie, Heinrich-Hein-Universistät, Dusseldorf Universität,Germany

Email

h.d.martin@yahoo.com

City

-

Orcid

-

Volume

16

Article Issue

2

Related Issue

24701

Issue Date

2007-12-01

Receive Date

2007-05-31

Publish Date

2007-12-01

Page Start

27

Page End

34

Print ISSN

1110-5089

Online ISSN

2356-9786

Article File

ZJPS_Volume 16_Issue 2_Pages 27-34.pdf

PDF . 2.4MB

Link

https://zjps.journals.ekb.eg/article_169384.html

Detail API

https://zjps.journals.ekb.eg/service?article_code=169384

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4

Type

Original Article

Type Code

862

Publication Type

Journal

Publication Title

Zagazig Journal of Pharmaceutical Sciences

Publication Link

https://zjps.journals.ekb.eg/

MainTitle

SYNTHESIS OF SOME MALEIMIDE DERIVATIVES VIA REGIO AND STEREOSELECTIVE REDUCTION USING SODIUM BOROHYDRIDE

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Article

Created At

22 Jan 2023