Abstract:
Objective: directed to evaluate to Effect of Casein Phospho PeptideAmorphous Calcium Phosphate on Some Salivary Ions Concentration in Children with Early Childhood Caries in comparison with the use CPP-ACPF and sodium fluoride 5% varnish.
Patients and methods: A total of 36 children with early child-caries (ECC), aged between 2.5-5 years were selected for this clinical trial study. Registered children were split into three groups at random according to the tested materials, group A; treated with non-fluoridated CPP-ACP-paste, group B; treated with CPP-ACPF-paste, and group C; treated with 5% sodium fluoride (NaF) paste. At first, 1 ml of unstimulated saliva was collected from whole enrolled children. In the next step, each tested material was applied on the tooth surfaces and then the saliva sampling was performed after 48 hours. The amount of phosphate ions was measured by spectrophotometer, while, calcium, and fluoride ions were measured by chromatographic device. Data were analyzed utilized paired t-test also used One-way ANOVA test at a p Results: This study revealed that; significant increase in phosphate and calcium ions condensation of the saliva before and after applying the CPP-ACP and CPP-ACPF pastes. However, the applying of CPP-ACPF paste, and 5% sodium fluoride paste significantly raise the fluoride scores of the saliva.
Conclusion: In this study, the utilize of CPP-ACP also the use of CPP-ACPF pastes can easily the remineralization of tooth surfaces and is beneficial for protecting the primary teeth.