Objective: Early Childhood Caries (ECC) considers a multifactorial disease. Vitamin D, calcium, and phosphorus have a crucial role in mineralized tissue formation and mineralization. The purpose of this study was to evaluate the association between the serum level of vitamin D, calcium, and phosphorus, and ECC in healthy preschool children.
Subject and methods: A 36 preschool children with age from 1 to 6 years old were selected for this clinical study. Enrolled children were randomly divided into two equal groups (n=18); group I; children with ECC, group II; children with caries-free. Clinical examination was carried out to assess decay, missing, filled teeth (dmft) caries index using World Health Organization (WHO) criteria. 25-hydroxyvitamin D “25(OH)D", calcium, and phosphorus in serum had been measured for all enrolled children. Data were analyzed using paired t-test, and chi-square test at a p Results: The results of this study showed a significant decrease in serum level of vitamin D, calcium, and phosphorus in children with ECC when compared to children with caries-free. However, the result of the dmft index revealed that the filled tooth due to caries showed a higher mean followed by decay and missing teeth.
Conclusion: There is a relation between the deficiency in serum level of vitamin D, calcium, and phosphorus and the incidence of ECC.