Objective: The aim of the present study was to make a clinical comparison of bracket position accuracy and failure rate between direct and indirect bonding techniques. Subjects and methods: Thirty patients were selected. Patients divided into two groups according to the technique, each group consist of 15 patients. Group A included the patients that treated with direct bonding technique. Group B included the patients that treated with indirect bonding technique. Check-up was carried out every 3 weeks and a special sheet was used to record the failure rate of the brackets. Results: 294 brackets were bonded in a group A (direct technique), and only 39 brackets were debonded. 290 brackets were bonded in a group B (indirect technique), and only 47 brackets were debonded. Conclusion: Generally, there is not clinically significance in the failure rate between direct and indirect bonding techniques.