Objective: This study aimed at evaluating the mandibular parameters as predictors for the gender and age using CBCT and panoramic radiograph. Materials and methods: Imaging exam records of 98 patients aged between 20 and 50 years, including Panoramic images and CBCT were selected. Selection was based on the exclusion of images with any kind of pathologic condition and fractures in the mandible. Results: Ramus height and gonial angel were used to differentiate females from males and estimate their ages. CBCT showed a statistically significant difference compared to panoramic radiography in Ramus height and gonial angel. In CBCT, when the ramus height was >61.5 mm it indicated the gender as females. When the Bigonial width was >155˚mm it indicated the gender as females. When the Gonial angel was ≥132˚ it indicated females. Concerning estimation of individuals ages in CBCT, when the ramous height was >61.5 mm it indicated ≤30 years old. When the Bigonial width was >155˚mm it indicated ≤30 years old. On the other hand, when the Gonial angel was ≥132˚ it indicated ≤30 years old.  Conclusion: Bigonial width and the Gonial angel on CBCT might differentiate females from males and predict different ages in a more superior and reliable way compared to panoramic view.