This study was to evaluate clinical and radiographic effects of three medicaments (Calcium hydroxide, Biodentine and BAG) on the pulp tissue of young permanent teeth. Methodology: Pulpotomy procedure was performed in thirty young first permanent molars. After that, the radicular pulp is medicated either with biodentine, BAG or Ca (OH)₂ and restored with Zn phosphate cement. After 48 Hours, 4 weeks, 3 months, patients were recalled and data were collected, tabulated, and statistically analyzed. Result: Clinical and radiographic assessments of the three groups revealed 90%, 60% and 80% success rates respectively, after 3 months follow up. Conclusion: Biodentine can be used successfully as a pulpotomy medicament in young permanent teeth.