Aim: To evaluate the mini-locking plate system in management of body mandibular fracture. Patient and methods: Twenty patients were randomly classified into two equal groups. Group (1): (The study group): Ten patients were treated by open reduction and internal fixation using single 2.0mm locking plate and arch bar as a tension band maintained for 5 weeks. Group (2): (The control group) Ten patients received the same treatment as in group (1) but with single 2.0mm conventional plate. Follow- up was performed for 6 months and post-operative complications such as infection, wound dehiscence, neurosensory disturbances and malocclusion were recorded. Arch bar was removed after 5 weeks of surgery. Data regarding age, sex, and bone density at the fracture side during healing, bite force measurements at anterior, premolar and molar regions were collected, tabulated and statistically analyzed using IBM SPSS software package version 20.0. Results: Uneventful healing of all fractures treated with mini-locking plates and conventional plate system, with no cases of malunion, nonunion, infection, or malocclusion being observed through the follow up periods. There was statistically difference between both groups regarding the mean bone density one week, 1, 3 and 6 months post-operatively. Bite force recording showed increasing values at subsequent follow ups corresponding to the healing of the fracture in both groups. Conclusion: Bone density in group (1) was in an accelerated pattern and of higher value than that of group (2). Patients treated with locking plate screw system regain more bite force compared to those treated with conventional miniplate screw system.