A field study was carried out during summer seasons of 2014 and 2015 at the Experimental Farm of the Faculty of Environmental Agricultural Sciences, El-Arish, Suez CanalUniversity.  It aims to study the effect of organic, bio and a mixture of natural mineral ore fertilizers on the productivity and quality of tomato fruits using local hybrid "Alisa" under sandy soil conditions using drip-irrigation system. The experiment included nine treatments as follows: T₁= 5.7 ton of compost/ fad. (40 kg N) + 80kg N/ fad., from ammonium sulfate (20.5% N) as control, T₂= 11.4 ton of compost/fad. (80kg N), T₃= 17.1 ton of compost/fad. (120kg N), T₄= 11.4 ton of compost/fad. (80kg N) + 1 ton mixture of natural mineral ore /fad., T₅= 17.1 ton of compost/fad. (120kg N) + 1 ton mixture of natural mineral ore /fad., T₆= 11.4 ton of compost/fad. (80kg N) + 400 g/fad. nitrogen fixing bacteria containing (NFB) Azotobacter chroococcum, T₇= 17.1 ton of compost/fad. (120kg N) + NFB, T₈= 11.4 ton of compost/fad. (80kg N) + 1 ton/fad. mixture of natural mineral ore, T₉=- 17.1 ton of compost/fad., (120kg N) + 1 ton/fad. mixture of natural mineral ore + NFB. Application of 17.1 ton of compost/fad. (120 kg N/fad.) + one ton/ fad., mixture of natural mineral ore + NFB recorded the highest significant values of total fresh and dry weight, leaf area/ plant, growth attributes, photosynthetic pigments, early and total yield as well as fruit quality.