The effect of foliar spraying with yeast extract and algae extract, as well as soil drench application with humic acid on some vegetative growth parameters, chlorophyll content and N, P, K% of Prime grape transplants grafted on Freedom and Paulsen rootstocks were studied during 2018 and 2019 seasons. A great effect on vegetative growth including stem height, stem diameter, number of lateral shoots/ plant, number of leaves/ plant, leaf area and root length were obtained with Prime grape transplants grafted on Freedom rootstock. All applied treatments were superior to control in improving growth parameters and the great effect was gained with combining treatment (T8) which including 0.2% yeast extract + 0.2% algae extract + 2.5 g/L./tree humic acid. However, the highest values of total chlorophyll, N and K% were obtained with Prime grape transplants grafted on Freedom rootstock, whereas P% values did not affect the type of rootstocks. Moreover, the highest values of total chlorophyll, N and P% were recorded by the combining treatment (T8) whereas; the highest K% values were obtained with 0.4% algae extract treatment. It could be concluded that Prime grape transplants grafted on Freedom rootstock were superior to Prime grape transplants grafted on Paulsen rootstock either on vegetative growth parameters or on some chemical constituents.