Two field experiments were carried out at the Experimental Farm and in the Laboratory of Horticulture Department Faculty of Agriculture at Moshtohor, Benha Univ., during 2015/2016 and 2016/2017 seasons to study the effect of some fertilizer treatments (organic and bio-fertilizers as well as their combination ) on vegetative growth and some chemical constituents of Moringa olifera plants. The treatments of bio-fertilizer were as follow: Control: without bio fertilizer treatments, One dose i.e., added during seed sowing, Two doses i.e., the first during seed sowing and the second after the first cut., Three doses i.e., the first during seed sowing, whereas the second after the first cut while the third one was added after the second cut. Whereas, the treatments of bio fertilizer were compost containing plant sources and cattle manure at the rate of 0.0, 5, 10 and 15m3/fed., was thoroughly mixed with the soil before planting. The obtained results showed that. The heaviest fresh and dry weights of moringa herb / plant were gained by 15 ton compost/fed.-fertilized plants, followed by 10ton compost/fed.-fertilized plants in the two seasons. Also, using the treatment of three doses showed to be the most effective one for inducing the highest fresh weight of herb, followed by the treatment of two doses in the two seasons. The combination of bio fertilizer at the high dose significantly induced the greatest values of plant height, particularly those treated with organic fertilizer at the highest concentration in the two seasons. The greatest values of branches and leaves number / plant were gained by the combinations of organic and bio fertilizers at the medium and high levels in the two seasons.