A potfactorial experiment was carried out to investigate the effect of plants inoculation by four levels from arbuscular mycorrhizal (AM) fungi spores (zero, 150, 300 and 450±10 spores plant ^-1) with six NPK fertilizer ratios (0:0:0, 0:10:5, 5:10:5, 10:5:5, 5:5:5 and 5:0:5) on the growth traits of Swieteina mahogany seedlings under sandy soil conditions.  The inoculums of AM fungi were used as mixed spores for one genus with three species Glomus mosseae, G. etunicatum and G. clarum. The results were shown that the high values in all plant growth parameters and NPK plant uptake in biomass were recorded at plant treated with NPK at ratio 10:05:05 in the presence of 450 AM spores plant¹. Also the high level of plant chlorophyll a; chlorophyll b and carotenoids were observed at plants treated with 300 AM spores plant^-1 at NPK ratio10:05:05. The AM spore's numbers were increased at NPK fertilization ratio 0:10:05 at all levels of inoculation. While the AM root colonization% was increased by increasing in both addition of nitrogen and phosphorus fertilization. The combination between AM fungi and NPK fertilization had better growth effect on increased NPK plant uptake when comparison between other treatments. The positive effects of plant inoculation only by AM fungi were helped S. mahagonito absorb more nutrients from soil more than plants free from AM treatment.