Yield and quality of white corn may be improved by manipulating the cultural practices to suit the crop with the prevailing environment. Therefore, two field experiments were carried out at AL-Frafra Oasis, New Valley Governorate, Egypt, in sandy clay loam soil, during the early summer seasons 2014 and 2015 growing seasons, to study the response of three corn hybrids of white corn and eightbio-mineral fertilizers treatments (a mixture of bio-fertilizer Rizobium and Aztobacter) and the percentages of recommended mineral fertilizer in the region as combination from mineral NPK on yield, it components and chemical contents on grains of white corn hybrids. Planting Single hybrid 30 K 8(SH30k8)caused an increase in all yield, and its components and grain chemical composition such as plant height (cm), ear length (cm), ear diameters (cm), no. of grains/ear, 100- grains weight (g), grain and biological yields (kg/fed), N(%),  P(%),  K(%) and crud protein  content( %) in both Seasons  except no. of ear/plant, stover yield and total carbohydrate ( %)in first season and P(%) in the second season. Results indicated that, adding F6 treatment led to significantly increased all parameters in both seasons, except no. of ear /plant, stover, crud protein and total carbohydrate in the first season and100 grains weight, grain yield, crud protein content and total carbohydrate (%) in the second season were significantly increased by adding F2 treatment. The interaction between white corn hybrids and Fertilizers on the yield, its components and grain chemical content. Results revealed that maximum criteria were obtained by (SH30k8) and F6 in first season. Similarly, results were obtained in second season except plant height and total carbohydrate were obtained by (SH30k8) and F2.