This work was conducted during 2016 and 2017 growing seasons in a commercial vineyard located in Abo-Ghaleb El-Giza Governorate Egypt for evaluating the effect of magnetic iron, Salicylic acid (SA) and Ascorbic acid (AsA) on growth and productivity of "Flame seedless" (Vitis vinifera L.) grapevines. The vines had eight years old, grown in sandy soil under drip irrigation system and spaced at 2 x 3m in row and between rows, respectively. Four magnetic iron levels (0, 150, 250 and 350g/vine) were applied as soil amendment once after winter pruning. Also, four foliar spray treatments (tap water, SA at 100, AsA at 150 and SA+ AsA at 100+ 150 mg/l, respectively) were applied two times (after fruit set and at veraison stage). The obtained results cleared that, the highest magnetic iron dose (350g/ vine) combined with the two antioxidants (SA+ AsA) was more effective in enhancing vine growth, yield and fruit quality parameters. Such combination treatment gave the highest significant values of growth characters in terms of leaf area, shoot length and leaf chlorophyll content as well as vine vigor parameters as internodes length, pruning's weight, the coefficient of wood ripening. Also, enhanced leaf nutrients content of N, P, K, Ca, Mg and Fe moreover, it was superior in reducing leaf Na, Cl and proline content. This combination treatment produced the highest yield/ vine, cluster weight, cluster length and best berries physical characters as berry diameter, length and volume as well as chemicals in terms of SSC%, SSC/acid ratio, anthocyanine pigments and reduced berry acidity. All magnetic iron applications were effective in reducing EC, pH and Sodium adsorption rate (SAR) of soil which partially elevate salinity hazer on vine growth and release more soil nutrients.