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279704

Impact of Advance techniques of radiotherapy on Organ at Risk dose distribution in treatment of Gastric cancer patient

Article

Last updated: 04 Jan 2025

Subjects

-

Tags

Basic and applied research of Chemistry,

Abstract

The goal of the current study was To compare different radiotherapy planning techniques for gastric cancer and impact of advance techniques on dose to OAR ( Organ at Risk ) . Materials and Methods A total of 20 gastric cancer patients were involved in current study and each patient was scheduled IMRT and VMAT techniques. Dose-volume histogram statistics, conformal index (CI), hand monitor units (MUs) were analyzed to compare treatment plans, treatment planning system eclipse Algorithm AXB with Energy true beam linear accelerator Varian model Results and Discussion The VMAT plans exceeded the IMRT technique for coverage planning tumor volume dose and reduction dose for organs at risk in the kidneys, but not in the liver. VMAT exhibited a better mean CI ( 0.89±0.03), than the other techniques. In addition, for the kidneys the dose sparing (V13, V18 and mean kidney dose) was improved by VMAT plans. However, IMRT showed a marginal advantage in V30 and mean dose in normal liver when compared with VMAT. The conclusion of this study suggest that VMAT provides improved tumor coverage when compared with IMRT, VMAT haven't no advantage in liver protection when compared with IMRT.

DOI

10.21608/bfszu.2022.129228.1149

Keywords

Gastric cancer, intensity-modulated radiotherapy, Volumetric modulated arc therapy, Organ at Risk Dose

Authors

First Name

eslam

Last Name

mohamed

MiddleName

mokhtar

Affiliation

physics department

Email

eslam.phy@gmail.com

City

-

Orcid

-

First Name

khaled

Last Name

elshahat

MiddleName

-

Affiliation

Al-Aznar University–Faculty of Medicine–Clinical Oncology Department - Cairo- Egypt

Email

khelshahat@yahoo.com

City

-

Orcid

-

First Name

mahmoud

Last Name

elghazaly

MiddleName

-

Affiliation

Physics Depart. –Faculty of Science- Zigzag University- Egypt

Email

ghazaly2000@yahoo.com

City

-

Orcid

-

Volume

2022

Article Issue

4

Related Issue

35751

Issue Date

2023-01-01

Receive Date

2022-08-04

Publish Date

2023-01-01

Page Start

31

Page End

38

Print ISSN

1110-1555

Link

https://bfszu.journals.ekb.eg/article_279704.html

Detail API

https://bfszu.journals.ekb.eg/service?article_code=279704

Order

3

Type

Original Article

Type Code

838

Publication Type

Journal

Publication Title

Bulletin of Faculty of Science, Zagazig University

Publication Link

https://bfszu.journals.ekb.eg/

MainTitle

Impact of Advance techniques of radiotherapy on Organ at Risk dose distribution in treatment of Gastric cancer patient

Details

Type

Article

Created At

22 Jan 2023