In the present work 4,6-diaryl-2-oxonicotinonitrile 1 reacts with serious of alkylating agents (ethyl bromoacetate, allyl bromide, propargyl bromide, chloroacetonitrile, chloroacetone, chloroacetic acid, epichlorohydrine, benzyl chloride, 1,3-dichloro isopropanol, 1,2-dichloroethane and 1,3-dibromopropane) by using K2CO3- NPs to form N-alkylated nicotinonitrile derivatives 2a-k. Also, the compounds 2j and 2k were reacted with another molecule of 2-oxonicotinonitrile 1 in the presence of K2CO3-NPs to afford the desired bis-pyridine ethane 4 and bi-pyridine propane 5, respectivelyIn the present work 4,6-diaryl-2-oxonicotinonitrile 1 reacts with serious of alkylating agents (ethyl bromoacetate, allyl bromide, propargyl bromide, chloroacetonitrile, chloroacetone, chloroacetic acid, epichlorohydrine, benzyl chloride, 1,3-dichloro isopropanol, 1,2-dichloroethane and 1,3-dibromopropane) by using K2CO3- NPs to form N-alkylated nicotinonitrile derivatives 2a-k. Also, the compounds 2j and 2k were reacted with another molecule of 2-oxonicotinonitrile 1 in the presence of K2CO3-NPs to afford the desired bis-pyridine ethane 4 and bi-pyridine propane 5, respectively.In the present work 4,6-diaryl-2-oxonicotinonitrile 1 reacts with serious of alkylating agents (ethyl bromoacetate, allyl bromide, propargyl bromide, chloroacetonitrile, chloroacetone, chloroacetic acid, epichlorohydrine, benzyl chloride, 1,3-dichloro isopropanol, 1,2-dichloroethane and 1,3-dibromopropane) by using K2CO3- NPs to form N-alkylated nicotinonitrile derivatives 2a-k. Also, the compounds 2j and 2k were reacted with another molecule of 2-oxonicotinonitrile 1 in the presence of K2CO3-NPs to afford the desired bis-pyridine ethane 4 and bi-pyridine propane 5, respectively.