Sub-basin quantitative morphometric analysis supplies insights into its dynamics, vulnerability to floods, erosion capacity and possible inherent relations to structural features. Various GIS tools with remote sensing data in an integrative manner are a useful approach to determine the morphological parameters of the basin. In the current study, we analyze the drainage system of three selected sub-basins namely: EL-Seih, Um graph and Mukattab, located in East Abu Zenima (EAZ) area, southwest Sinai, Egypt. The present study concentrates on terrain (slope and aspect), drainage network, watershed geometry, drainage texture analysis and relief characteristic aspects of the three sub-basins. Slope and aspect maps of the sub-basins indicate the variety in there topographic surface. The morphometric analysis results revealed that the sub-basins are at late youth stage, faintly potential to soil erosion and flooding, low to moderate runoff rate and the geological structures do not deform the drainage pattern, except for W El-Seih. The present study indicates that the morphometric analysis is highly applicable in delineating water supply zones.