The utilization of thioxouracil 1 as a precursor for the synthesis of some novel functionalized and annulated azines was reported here, thus amination of compound 1 afforded diaminopyrimidine scaffold 3 which upon treatment with benzoyl isothiocyanate furnished functionalized pyrimidine 5. Also, diazotization of 3 yielded tetrazolopyrimidine 7. The structures of the newly synthesized compounds were confirmed by different spectral tools.
The utilization of thioxouracil 1 as a precursor for the synthesis of some novel functionalized and annulated azines was reported here, thus amination of compound 1 afforded diaminopyrimidine scaffold 3 which upon treatment with benzoyl isothiocyanate furnished functionalized pyrimidine 5. Also, diazotization of 3 yielded tetrazolopyrimidine 7. The structures of the newly synthesized compounds were confirmed by different spectral tools.
The utilization of thioxouracil 1 as a precursor for the synthesis of some novel functionalized and annulated azines was reported here, thus amination of compound 1 afforded diaminopyrimidine scaffold 3 which upon treatment with benzoyl isothiocyanate furnished functionalized pyrimidine 5. Also, diazotization of 3 yielded tetrazolopyrimidine 7. The structures of the newly synthesized compounds were confirmed by different spectral tools.