The present study is an attempt to delineate the regional structural framework and basin configuration of Northern Nile Delta, Egypt by analysis of gravity map. The study area is located, between Longitude 30o 30′′ - 32o00′′ E and Latitude 31o 00′′ - 31o 48′′ N. The least square polynomial technique is used to separate the Bouguer anomaly of the study area into its regional and residual components. The second order polynomial is taken as the optimum one to achieve the regional residual separation. The structural framework of the sedimentary basins is delineated using the Euler deconvelution technique, the detected fault systems are grouped into six major tectonic trends: Mediterranean trend (E-W trend), Syrian arc trend (N 45o - 65o E trend), Najd trend (N 65o W trend), Gulf of Suez trend (N 35o - 45o W trend), Aqaba trend (N 15o - 25o E trend) and North African trend (N-S trend). The constructed depth to the basement map illustrates a huge basin located in the central part of the study area. The depth ranges from 1400 m to 10460 m.