Background: vocational students considered young workers that are usually injured at worksite. Education and awareness programs to prevent those injuries among them are common and always effective. Aim of the study: To evaluate the effect of Occupational Hazards prevention Program among Vocational Education's Students in Zagazig City. Subject and Method: Research design: A quasi-experimental research design [pretest -posttest] was used. Setting: At the vocational educational school of El Sayadeen, at Zagzig City. Subject: A convenience sample consisted of 82 students. Tools of data collection: three tools were used; Interview Questionnaire sheet, Students' knowledge about occupational hazards, and Child labor's practices regarding the occupational health hazards of the work place. Results: The mean age of the students was 16.15 ± 0.749 yeaes, 41.46% of them were at their first grade in the school, and about 68.29% of them were from rural areas. Also, there were statistically significant totally improvements in the students' knowledge and practices regarding occupational hazards at (p<0.001) in the post-intervention phase. There were highly statistically significant positive correlation among students' total knowledge and practices pre and post-test (r =0.732, 0.587) respectively. Conclusion: The applying of Occupational Hazards prevention Program among Vocational Education's Students was effective in enhancing their knowledge, and practices. Recommendation: Comparative studies to show effectiveness of various teaching methods can be assessed and even attitude dimension can also be assessed.