Background: Depressive symptoms among the students' college has been identified as a serious health concern and has been linked to a multitude of health problems such as alcohol and substance abuse. Aim of the study: was to determine relation between level of depressive symptoms and social support among students at Faculty of Nursing. Subjects & methods: Research design: A descriptive design was used. Setting : the present study was conducted at the Faculty of Nursing, Zagazig University. Subjects: Two hundred and ten from nursing students were enrolled in the present study. Tools of data collection: Socio-demographic data sheet, Beck Depression Inventory Scale and Multidimensional scale of Perceived Social Support. Results: the present study showed that more than half of the studied sample had considerable depressive symptoms (moderate –severe depression) and the majority of the studied sample had adequate social support .There was highly significant negative correlation between depressive symptoms and social support, as group with considerable depressive symptoms had in adequate social support. Conclusion: Based on the findings of the present study , concluded that social support had positive impact in lowering level of depressive symptoms .Recommendations: The study recommended that, establishing psychosocial counseling center or psychiatric clinic at Faculty of Nursing to assist students to handle issues that constitute a source of stress in their life