Background: Gastrointestinal (GI) endoscopy is an important tool for the identification and
treatment disorders of the gastrointestinal tract. Thorough understanding of infection control
and its application to GI endoscopy is crucial to prevent lapses in reprocessing and the
possibility of transmission of infection (Nelson, DB.2003). Aim of the study: The aim of this
study was to evaluation the effect of infection control training program on nurse's
performance and microbial results on GIT Endoscopes. Setting & Subjects: It was conducted
at Elnaser Insurance Hospital at Helwan City in Egypt. Purposive sample included all
available (40) nurses, and 5 GIT endoscopes. Study tools: Tools used for data collection
included self-administered questionnaire sheet, an observation checklist, and microbiological
assessment sheet. Results: The mean ± SD age of the studied nurses were 29.5 ±5.76, about
two thirds were female and diploma nurse, and more than phases, these indicated for decrease
the presence of microbial infection. Conclusion: there were a statistical significance
difference between pre implementation of infection control training program and post
implementation the endoscopic reprocessing program lead to improve nurses' knowledge and
skills as well as decrease the incidence of microbial infection transmission through GIT three
years of experience, these experience from working, There was a highly significant difference
in nurses' level of knowledge and skills as well as microbiological testes throughout the study
endoscope. Recommendations: Continuous educational infection control training programs
are recommended. So incorporation of such interventions apply in all endoscope unite all over
Egypt.