Background: Hypertension forms a major public health problem in the world. Compliance
toward different therapeutic regimen is a key factor in controlling blood pressure. Aim of study
was to assess factors affecting compliance of patients with essential hypertension toward
therapeutic regimen. Research design & setting: A descriptive exploratory design was utilized
in this study at the Outpatient Clinic at Medical Specialist Hospital, Mansoura University.
Sample: A convenience sample of all available adults from both sex and aged 20-60 years
diagnosed as essential hypertension and on antihypertensive treatment were recruited for the
current study, through assessment of patients' socio-demographic characteristics, knowledge,
practice, compliance through Hill Bone Scale, and factors affecting their compliance. Results:
The findings of the present study revealed that: Most of the studied sample had unsatisfactory
knowledge score about hypertension, more than three quarters of them were noncompliance
toward different therapeutic regimen. The social support, economic and psychological factors
affected the majority of the studied sample Conclusion: The study concluded that compliance
with therapeutic regimen in patient with essential hypertension influenced significantly by
socio-demographic characteristics, while it was not influenced by their knowledge about
hypertension. Recommendation: The study recommended that development of educational
program for patient with essential hypertension about life style modifications and different
aspects of treatment regimen and how to be compliant with it.