Background: Pre-eclampsia (PE) is a disease with worldwide significance to mothers and
infants; it may have health hazards that increase maternal, fetal and infant morbidity and
mortality. Aim of the present study was to evaluate the maternal and neonatal outcomes of
pregnancy associated with pre-eclampsia. Sample& setting: A case-control prospective
study was selected in carrying out this study and a representative sample of two groups, one
from women diagnosed with pre-eclampsia (100) and the other from normotensive women
(100), were admitted to Zagazig University maternity hospital. Tools used for data collection
were; an interview questionnaire sheet, a Clinical assessment form, Ultrasonography, Cardio-
Tocography, Partograph, a Summary of labor sheet, a Problems-encountered sheet and a
Neonatal assessment sheet. Results of present study revealed that, the incidence of preeclampsia
were higher among younger women (<25) and older (35+) than normotensive
women. Cesarean section rates were significantly higher in the group with pre-eclampsia than
in the control group (p < 0.05). Low Apgar score, low birth weight, more admission to the
NICU as well as newborn deaths were significantly higher among the pre-eclamptic group (p
= 0.000). It can be concluded that, lower gestational age, less parity, higher cesarean section
rate, low Apgar score and low birth weight neonates were more frequent in pre-eclamptic
women than in healthy pregnant women. The study recommended that: written clinical
guideline or nursing protocol for the management of patient with pre-eclampsia should be
developed and used by the nursing staff. Improving quality of ante-natal care for women with
preeclampsia is highly recommended at Zagazig university hospitals.