Background: Case-based Teachings is an active learning strategy in which students read and discuss
complex real-life situations that call on their analytical thinking skills and decision-making. Aim of the
study: To assess the opinions of nursing students about case-based teaching versus traditional lecturebased
method. Subjects and Methods: Research design: A descriptive study was utilized in this study.
Setting: Faculty of Nursing, Sohag University. Subjects: Include a representative sample (183) from the
total number of students. Tool of data collection: Students Opinions Questionnaire. Results: The most
important characteristic of the case-based teaching methods was increased reading of comprehension
and collaboration skills during the teaching process. In addition, the majority of the students agreed that
case-based teaching method decreased monotonous situation of the classroom, increased knowledge
retention and self-esteem compared with lecture. Of these, 71.8% they were highly satisfied with this new
method. However, no differences were observed between the students satisfaction based on gender
(p>0.05). On the other hand, it was found a significant difference in all mean scores of age ˃21 years
except in the following dimensions: motivation to study, reflective and critical thinking and imagination
skills. Conclusion: Case-based teaching method has high efficacy and more accepted by the students
than lecture in understanding the topic. Recommendations: this is simply an applicable method and
reduced of monotonous situation of the classrooms. Therefore, nursing educators must use this method
to promote active learning among the students.