Background: Nocturnal enuresis leads to an inability to control urination during sleep. The aim of the study: Assess predisposing factors, body image and self-esteem among school age children with nocturnal enuresis. Subjects & methods: Research design: Case-control study design was used. Setting: the Urology and the Psychiatric Outpatient clinics at Zagazig University hospital and Al -Ahrar hospital at Zaga-zig city. Subjects: The study was conducted on 240 children with their mothers (120 studies, and 120 con-trols). Tools of data collection: Three tools were used; Structured interview questionnaire sheet, body image scale and self-esteem scale. Results: Concerning to the mean of total self-esteem of both studied and control group were 39.00± 3.82 and 43.22± 4.77 respectively. In addition to the mean of overall image of both studied and control group were74.8± 4.4 and 79.8± 5.0 respectively. Conclusion: Concerning the overall image and self-esteem, there are statistically significant differences between both control and stud-ied group. Recommendations: Don't punish the child for bedwetting, give the child a simple reward like a coin every time when he wakes up without wetting and trained him during day to urinate to increase the bladder capacity