The present paper solves the arrangement of the wing and fuselage structures with respect to the relative position of the large cutouts in both airframe parts. The finite element method based on displacement field is used for the analysis of wing structure ,while the matrix force method as given by Prof. Argyris is used for the analysis of fuselage structure. A computer program for the combined displacement-force method is constructed. Numerical examples, representing different arrangements are included which illustrate the application of the method to practical problems.The ciculated results are compared with those obtained by measurements.