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187835

Ventricular Function and Pulmonary Artery Pressure in Children with Mild and Moderate Bronchial Asthma

Article

Last updated: 24 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Pediatrics

Abstract

Background: Bronchial asthma is a chronic airway disease. Cardiac affection in children with bronchial asthma was reported mainly in cases with severe asthma and during acute exacerbations.
Aim of the Work: To study cardiac affection in children with mild and moderate bronchial asthma using conventional and tissue Doppler imaging [TDI] echocardiography.
Patients and Methods: This was a prospective case control study. Study involved 160 children aged 6-14 years old who were following in outpatient pediatric clinic, Al-Hussein hospital, Al-Azhar University, Cairo, Egypt, during the period from January 4, 2016, till February 15, 2017. All children underwent peak expiratory flow rate [PEFR] assessment. Echocardiography was done for all to assess systolic and diastolic functions of right ventricle [RV] and left ventricle [LV] using conventional and tissue Doppler imaging [TDI] echocardiography.
Results: TDI parameters showed evidence of RV diastolic dysfunction in patients with moderate asthma in the form of significantly lower tricuspid valve [TV] e' [12.1 ± 2.7 cm/s], lower TV e'/a' ratio [1.28 ± 0.18], prolonged RV isovolumetric relaxation time [IVRT] [71.8 ± 2.4 ms], and higher RV myocardial performance index [0.49 ± 0.04] compared to control group.  Also, patients with mild asthma had impaired RV diastolic function in the form of significantly lower TV e'/a' [1.51 ± 0.13] and longer RV IVRT [65 ± 2.9 ms] compared to control group. Pulmonary artery pressure was significantly elevated in moderate asthma group [18.4 ± 9.2 mmHg]. RV IVRT was the only parameter showing a significant negative correlation to PEFR
Conclusion: Pediatric patients with mild and moderate bronchial asthma may have RV diastolic dysfunction. TDI is a good screening tool to detect early changes in cardiac function in such patients. RV IVRT measured by TDI is a sensitive tool to detect early diastolic impairment. 

DOI

10.21608/ijma.2021.187835

Keywords

bronchial asthma, children, Ventricular function, Tissue Doppler imaging, Pulmonary Artery Pressure

Authors

First Name

Tarek Kotb

Last Name

Alsayad

MiddleName

-

Affiliation

Department of Pediatrics, Pediatric Cardiology Division, Faculty of Medicine, Al-Azhar University, Egypt

Email

elsayadtarek@gmail.com

City

Cairo

Orcid

0000- 0002-9655-6067

First Name

Saad Ahmed

Last Name

Mohamed

MiddleName

-

Affiliation

Department of Pediatrics, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

saad.am.pedia@gmail.com

City

Damietta

Orcid

-

Volume

3

Article Issue

3

Related Issue

27050

Issue Date

2021-07-01

Receive Date

2021-05-21

Publish Date

2021-07-01

Page Start

1,754

Page End

1,760

Print ISSN

2636-4174

Online ISSN

2682-3780

Article File

IJMA_Volume 3_Issue 3_Pages 1754-1760.pdf

PDF . 1.7MB

Link

https://ijma.journals.ekb.eg/article_187835.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=187835

Order

187,835

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

Ventricular Function and Pulmonary Artery Pressure in Children with Mild and Moderate Bronchial Asthma

Details

Type

Article

Created At

22 Jan 2023