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186029

Correlation between Iron Status and Simple Febrile Seizures in Children

Article

Last updated: 22 Jan 2023

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Subjects

-

Tags

Pediatrics

Abstract

Background: Febrile seizures are non-epileptic types of seizure that occur frequently during early childhood. Multiple factors are implicated in the pathogenesis of these types of seizures. Iron deficiency might play as an etiological or, at least, augmenting factor in the development of febrile seizures.
Objective: To study iron status among children with simple febrile seizures, and to estimate the prevalence of iron deficiency between them.
Patients and methods: A case-control study included 100 febrile children aged 6 months to 60 months, and were ascribed to 2 groups; 50 children with simple febrile seizures [case group], and 50 children who had febrile disease without occurrence of seizures [control group]. Venous samples were obtained for the analysis of complete blood count, and iron indices [serum ferritin, serum iron and total iron binding capacity].
Results: The peak temperature was significantly elevated among the case group [P=0.03]. Regarding iron profile, compared to controls, the case group had significantly lower iron [54.24±16.04 vs. 62.6±16.02; P=0.011], and lower ferritin [37.612±19.85 vs. 80.624±31.57; P <0.001]. Correlation analysis revealed a significant negative correlation between serum ferritin and frequency of febrile seizures [P=0.025]
Conclusions: Iron deficiency and iron deficiency anemia were more common among children with simple febrile seizures, and they were associated with increase in the duration and frequency of seizures. Special attention should be paid for the assessment of iron status among children with febrile seizures.

DOI

10.21608/ijma.2021.79064.1320

Keywords

Fever, Seizures, iron, Anemia, febrile seizures

Authors

First Name

Marwa

Last Name

Elkafafy

MiddleName

-

Affiliation

Department of Pediatrics, EL-Raml Pediatric Hospital, Ministry of Health, Egypt

Email

marwa11.pediatrics@domazhermedicine.edu.eg

City

-

Orcid

-

First Name

Magdy

Last Name

Sakr

MiddleName

Mohamed Ashmawy

Affiliation

Department of Pediatrics, Damietta Faculty of Medicine, AL-Azhar University, Egypt

Email

sakrmagdy@hotmail.com

City

Cairo

Orcid

-

First Name

Mohamed

Last Name

Elsamanoudy

MiddleName

Ibrahim

Affiliation

Department of Pediatrics, Damietta Faculty of Medicine, AL-Azhar University, Egypt

Email

mohamed_elsamanody@yahoo.com

City

tanta

Orcid

27801011202238

First Name

hesham

Last Name

abd al-samee

MiddleName

samir

Affiliation

Department of Clinical Pathology, Damietta Faculty of Medicine, AL-Azhar University, Egypt

Email

dr.hesham012@gmail.com

City

-

Orcid

27608151100155

Volume

3

Article Issue

3

Related Issue

27050

Issue Date

2021-07-01

Receive Date

2021-06-04

Publish Date

2021-07-01

Page Start

1,714

Page End

1,718

Print ISSN

2636-4174

Online ISSN

2682-3780

Article File

IJMA_Volume 3_Issue 3_Pages 1714-1718.pdf

PDF . 1.5MB

Link

https://ijma.journals.ekb.eg/article_186029.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=186029

Order

30

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023