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Magnesium Sulfate versus Tramadol as Adjuvants to Lidocaine in Intravenous Regional Anesthesia for Carpal Tunnel Release Surgery: A Randomized Clinical Study

Article

Last updated: 04 Jan 2025

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Subjects

-

Tags

Surgery

Abstract

Background: Intravenous regional anesthesia [IVRA] is a simple and effective anesthetic method for providing regional anesthesia of the upper limbs during carpal tunnel release surgery [CTRS]. However, the procedure is associated with significant postoperative pain and adjuvant analgesic agents are recommended.
The Aim of The Work: This study aimed to compare the analgesic effects of magnesium sulfate and tramadol when added to lidocaine for IVRA during CTRS.
Methods: In this double-blinded, randomized clinical trial, 60 ASA I-II patients eligible for elective CTRS with IVRA were randomly allocated into one of 3 groups. The first group [lidocaine group] received IVRA with 40 ml lidocaine 0.5%. The second group [lidocaine + tramadol group] received IVRA with40 ml 0.5% lidocaine and tramadol 1mg/kg. The third group [lidocaine + magnesium sulphate group] received IVRA with 40 ml 0.5% lidocaine and magnesium sulfate 10 mg/kg and normal saline. Outcome parameters included time to onset of sensory and motor block, time to onset of tourniquet pain, need of intra-operative analgesia, intraoperative consumption of fentanyl, duration of postoperative analgesia and pain intensity were noted in each patient.
Results: Comparison between the studied groups regarding the outcome parameters. The Lidocaine + Tramadol and the Lidocaine + Magnesium groups achieved better performance in all the studied parameters in comparison to the Lidocaine group. In addition, Lidocaine + Tramadol groups had significantly better performance in comparison to the Lidocaine + Magnesium group. No significant differences were reported between the studied groups regarding post-operative complications
Conclusions: Use of tramadol and magnesium sulphate as adjuvants to lidocaine achieved better performance in all the studied parameters in comparison to the lidocaine only. In addition, tramadol had significantly better performance in comparison to magnesium sulphate without significant side effects. 

DOI

10.21608/ijma.2021.72475.1299

Keywords

magnesium sulfate, tramadol, Intravenous regional anesthesia, Carpal Tunnel Release Surgery

Authors

First Name

Khaled

Last Name

Elsheshtawy

MiddleName

-

Affiliation

Department of Anesthesia and Intensive Care, Faculty of Medicine, Al-Azhar University

Email

khaledshrief2@gmail.com

City

-

Orcid

-

First Name

Ahmed

Last Name

Elsawy

MiddleName

Gamal

Affiliation

Department of Anesthesia and Intensive Care, Faculty of Medicine, Al-Azhar University

Email

drahmedelsawy@azhar.edu.eg

City

cairo

Orcid

0000-0001-7075-7963

First Name

Ahmed

Last Name

Abouelnasr Khalifa

MiddleName

Maher

Affiliation

Department of Anesthesia and Intensive Care, Faculty of Medicine, Al-Azhar University

Email

ahmed.maher101@azhar.edu.eg

City

-

Orcid

-

Volume

3

Article Issue

3

Related Issue

27050

Issue Date

2021-07-01

Receive Date

2021-04-15

Publish Date

2021-07-01

Page Start

1,708

Page End

1,713

Print ISSN

2636-4174

Online ISSN

2682-3780

Article File

IJMA_Volume 3_Issue 3_Pages 1708-1713.pdf

PDF . 1.9MB

Link

https://ijma.journals.ekb.eg/article_186028.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=186028

Order

29

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

Magnesium Sulfate versus Tramadol as Adjuvants to Lidocaine in Intravenous Regional Anesthesia for Carpal Tunnel Release Surgery: A Randomized Clinical Study

Details

Type

Article

Created At

22 Jan 2023