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160238

Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction with ST Segment-Elevation: Effect on the Severity of Ischemic Mitral Regurgitation

Article

Last updated: 24 Dec 2024

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-

Tags

Internal Medicine

Abstract

Background: Myocardial infarction is a daily challenging emergency. Proper diagnosis and intervention in a timely manner is crucial.   
The aim of the work: We aimed to detect the impact of primary percutaneous coronary intervention [PPCI] on the development and severity of mitral valve regurgitation in patients presenting with acute myocardial infarction with ST-segment elevation [STEMI].
Patients and Methods: This was a cross-sectional comparative study that was conducted from January 2018 to November 2019 at the Department of Cardiology, Al-Azhar University Hospital, Damietta, Egypt. Patients were divided into four groups; Group I: STEMI patients with PPCI and single-vessel disease; Group II: STEMI patients with PPCI of culprit vessel and staged PCI with in-hospital admission; Group III: STEMI patients with streptokinase and pharmaco-invasive PCI of the single vessel; Group IV: STEMI patients with streptokinase and multi-vessel PCI at the same session.
Results: One-hundred and five patients were included in this study. Patients in group I showed a significant improvement after six months of follow-up in terms of ejection fraction [p <0.001]. Regarding the coaptation height, it showed a significant elevation in group I [p <0.001], and a significant reduction in group II [p <0.001] and III [p=0.013]. Similarly, PISA reduced significantly after six months in group I [p <0.001], II [p=0.002], and IV [p=0.007]. EPSS was reduced significantly in group I [p=0.0004]. Likewise, the distance of intrapapillary showed a significant reduction in group I [p <0.001]. Regarding the regurgitant area, it was significantly [p <0.05] reduced in all groups.
Conclusion: Our results showed that PPCI could decrease the incidence and the severity of IMR and improve IMR parameters, especially in patients with acute STEMI. Further well-designed longitudinal studies with a larger sample size are required to evaluate these findings.

DOI

10.21608/ijma.2021.50324.1210

Keywords

Primary PCI, STEMI, Acute myocardial infarction, Ischemic Mitral Regurgitation

Authors

First Name

Mohammad Aly

Last Name

Hammad

MiddleName

-

Affiliation

Department of Cardiology, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

mh2353820@gmail.com

City

Kafr Elsheikh

Orcid

-

First Name

Mansour Mohammad

Last Name

Mustafa

MiddleName

-

Affiliation

Department of Cardiology, Faculty of Medicine, Al-Azhar University, Egypt

Email

mans_aref@yahoo.com

City

Cairo

Orcid

-

First Name

Mohamed Adel

Last Name

Attia

MiddleName

-

Affiliation

Department of Cardiology, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

cardioadel2003@yahoo.com

City

-

Orcid

-

First Name

Muhammad Saad

Last Name

Reihan

MiddleName

-

Affiliation

Department of Cardiology, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

mreihan@gc.edu.sa

City

Jeddah

Orcid

-

First Name

Ebrahim Farajallah

Last Name

Said

MiddleName

-

Affiliation

Department of Cardiology, Faculty of Medicine, Al-Azhar University, Egypt

Email

ebrahim_faragallah@gmail.com

City

Cairo

Orcid

-

Volume

3

Article Issue

2

Related Issue

24821

Issue Date

2021-04-01

Receive Date

2020-11-18

Publish Date

2021-04-01

Page Start

1,437

Page End

1,446

Print ISSN

2636-4174

Online ISSN

2682-3780

Article File

IJMA_Volume 3_Issue 2_Pages 1437-1446.pdf

PDF . 1.3MB

Link

https://ijma.journals.ekb.eg/article_160238.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=160238

Order

35

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction with ST Segment-Elevation: Effect on the Severity of Ischemic Mitral Regurgitation

Details

Type

Article

Created At

22 Jan 2023