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158325

Assessment of Suprachoroidal Injection of Triamcinolone Acetonide in Cases of Diabetic Macular Edema

Article

Last updated: 22 Jan 2023

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-

Tags

Ophthalmology

Abstract

Background: Diabetic retinopathy [DR] remains one of the main causes of visual reduction in the world. The visual reduction in patients with DR is usually due to diabetic macular edema [DME].Suprachoroidal triamcinolone acetonide injection is a new effective modality used for the management of diabetic macular edema.
The aim of the work: To assess the visual acuity [VA], central macular thickness [CMT] by optical coherence tomography [OCT] and intraocular pressure [IOP] measurement in patients with DME injected with Triamcinolone Acetonide through suprachoroidal space.
Patients and Methods: Forty eyes of 37 patients [18 males and 19 females]] with DME were included and followed-up for 6 months to assess VA, CMT and IOP. Patients were included if they were diagnosed as DME. 
Results: Baseline measurements were logMAR best corrected visual acuity [VA] which was 0.83 ± 0.09, [OCT] which was 422.42 ± 64.1 µm and [IOP] which was 15.25 ± 1.46 mmHg. Post injection measurements of VA during the four points of the follow-up period showed statistically significant improvement. At one-week post-injection,  logMAR VA was 0.82 ± 0.09, at one-month follow-up was 0.72 ± 0.09, at three months was 0.68 ± 0.1, at six months, was 0.62 ± 0.1,. OCT follow-up measurements showed highly significant improvements, which started from the first week post-injection till the end of the follow-up period at six months point. At one week, it measured 391.7 ± 60.6 µm, at one month the measurement was 337.1 ± 54.5 µm, at three months was 302.7 ± 46.5, at six months, was 267.9 ± 40.7.
Conclusion: Injection of TA to the suprachoroidal space in DME, was well tolerated without any serious ocular adverse events and produced significant resolution in CST and significant improvement in BCVA.

DOI

10.21608/ijma.2021.55079.1230

Keywords

Keywords: Diabetic, macular edema, Triamcinolone acetonide, Suprachoroidal space, Optical Coherence Tomography

Authors

First Name

Mahmoud Samy

Last Name

Yousef

MiddleName

-

Affiliation

Department of Ophthalmology, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

mahmoudsamy217@gmail.com

City

Mahalla Alkobra

Orcid

-

First Name

Yonis

Last Name

Abd Elhafez

MiddleName

Alsaeid

Affiliation

Department of Ophthalmology, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

yonis_abdelhafez@yahoo.com

City

Damieta

Orcid

-

First Name

Mohamed

Last Name

Farag

MiddleName

Hassanein

Affiliation

Department of Ophthalmology, Faculty of Medicine, Al-Azhar University, Egypt

Email

moh_hassanin@hotmail.com

City

Cairo

Orcid

-

Volume

3

Article Issue

2

Related Issue

24821

Issue Date

2021-04-01

Receive Date

2020-12-26

Publish Date

2021-04-01

Page Start

1,384

Page End

1,389

Print ISSN

2636-4174

Online ISSN

2682-3780

Article File

IJMA_Volume 3_Issue 2_Pages 1384-1389.pdf

PDF . 1.4MB

Link

https://ijma.journals.ekb.eg/article_158325.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=158325

Order

28

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023