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158047

Predictors of Malignancy in Thyroid Nodules

Article

Last updated: 04 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Surgery

Abstract

Background: Better and early prediction of malignant thyroid nodule, and sure differentiation from benign one, is crucial need to decrease the rate of non-indicated surgeries.
The aim of the work: To find risk factors and predictors of malignancy in patients with thyroid nodule[s].
Patients and Methods:Fifty patients with thyroid nodule[s] were included. All patients were evaluated by history taking, clinical examination and laboratory investigations. Imaging studies included thyroid ultrasound [US]. All were also submitted to fine needle aspiration cytology [FNAC] before treatment by total or subtotal thyroidectomy. Excised tissues were sent to histopathological analysis.
Results:The incidence of malignancy was 22.0%. both benign and malignant groups were comparable as patient characteristics, complaints except the significant increase in cosmetic disfigurement among patients with benign nodules [92.3% vs. 45.5%].Patients with malignant nodules had a significant increase of ill-defined margins, intranodular vascularity and enlarged lymph nodes [72.7%, 63.6% and 72.7% vs 5.1%, 12.8% and 25.6% respectively].  Ill-defined margins, enlarged lymph node and high grade in FNAC were the predictors of thyroid malignancy.
Conclusion: Predictors of malignant thyroid nodules are ill- defined edges, enlarged lymph node and high grade in FNAC. This helps clinicians to spare more benign cases from surgical interference.

DOI

10.21608/ijma.2021.43700.1178

Keywords

THYROID, malignant, benign, Ultrasound, Predictor

Authors

First Name

Abdel Rahman Ahmed

Last Name

Mohamed Ragab

MiddleName

-

Affiliation

Department of Surgery, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

abdel.ragab2015@domazhermedicine.edu.eg

City

Manzalah

Orcid

-

First Name

Ahmed Salama

Last Name

Sayouh

MiddleName

-

Affiliation

Department of Surgery, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

asalama2000@domazhermedicine.edu.eg

City

New Damietta

Orcid

-

First Name

Amr Abdel Ghany

Last Name

Sarhan

MiddleName

-

Affiliation

Department of Surgery, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

amro_sarhan@domazhermedicine.edu.eg

City

Mansura

Orcid

-

Volume

3

Article Issue

2

Related Issue

24821

Issue Date

2021-04-01

Receive Date

2020-09-21

Publish Date

2021-04-01

Page Start

1,369

Page End

1,376

Print ISSN

2636-4174

Online ISSN

2682-3780

Article File

IJMA_Volume 3_Issue 2_Pages 1369-1376.pdf

PDF . 1.2MB

Link

https://ijma.journals.ekb.eg/article_158047.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=158047

Order

26

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

Predictors of Malignancy in Thyroid Nodules

Details

Type

Article

Created At

22 Jan 2023