ManageChatDiscover
152307

The Role of Multi-Detector Computed Tomography in Assessment of Chron’s Disease Progression: A Cross-sectional Study

Article

Last updated: 04 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Internal Medicine

Abstract

Background:There is a lack of information regarding the correlation between multi-detector computed tomography [MDCT] findings and clinical activity of Chron's disease.
The aim of the work: In this study, we aimed to investigate the correlation between MDCT and the degree of activity of Chron's disease [CD].
Patients and Methods: In this prospective study, a total of 50 patients with CD were recruited The disease activity was assessed using the Crohn's Disease Activity Index [CDAI]. For MDCT evaluation, we used 256 Multislice CT scanners [Toshiba Medical System, Tochigi-ken, Japan].
Results: Forty-five patients [90%] showed signs of activity, while the other five patients [10%] were in the remission state [showed no signs of activity]. The most common sign of activity was mucosal hyper enhancement [93.3%], followed by mucosal thickening [91%], mesenteric congestion [64.4%], and mesenteric lymphadenopathy [33.3%].  The association analysis showed that there was a statistically significant association between CDAI and signs of activity in MDCT [360 ±64.5 in patients with signs of activity vs. 206.9 ±145.6 in patients with no signs of activity; p <0.001]. In addition, there were statistically significant associations between CDAI and presence of complications and extra-intestinal involvement [p >0.05].
Conclusion: Our study showed that the findings of MDCT are significantly correlated with clinical activity score. Clinical and radiological predictors of sever disease need to be assessed as predictors in future studies

DOI

10.21608/ijma.2021.56535.1240

Keywords

Chron’s Disease, Activity Score, MDCT, Multi-detector slices, Enterography

Authors

First Name

Fadila

Last Name

Elsayed

MiddleName

Mamdouh

Affiliation

Department of Radiology, Faculty of Medicine for Girls, Al-Azhar University, Egypt

Email

fadilaeed1999@azhar.edu.eg

City

-

Orcid

-

First Name

Eman

Last Name

Nassef

MiddleName

Mostafa

Affiliation

Department of Internal Medicine, Faculty of Medicine for Girls, Al-Azhar University, Egypt

Email

nassef.eman@yahoo.com

City

-

Orcid

-

First Name

Neamat

Last Name

Abdelmageed

MiddleName

Abdelmageed

Affiliation

Department of Hepatogastroentrology and Infectious Diseases, Faculty of Medicine for Girls, Al-Azhar University, Egypt

Email

dr.neamatabdelmageed@yahoo.com

City

-

Orcid

-

Volume

3

Article Issue

2

Related Issue

24821

Issue Date

2021-04-01

Receive Date

2021-01-04

Publish Date

2021-04-01

Page Start

1,240

Page End

1,246

Print ISSN

2636-4174

Online ISSN

2682-3780

Article File

IJMA_Volume 3_Issue 2_Pages 1240-1246.pdf

PDF . 1.4MB

Link

https://ijma.journals.ekb.eg/article_152307.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=152307

Order

11

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

The Role of Multi-Detector Computed Tomography in Assessment of Chron’s Disease Progression: A Cross-sectional Study

Details

Type

Article

Created At

22 Jan 2023