Beta
ManageSearchChatDiscover
124226

Relation between Iron Status and Hemoglobin A1c in Children with Type-1 Diabetes Mellitus

Article

Last updated: 24 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Pediatrics

Abstract

Background: Hemoglobin A1c [HbA1c] is the best standard for measurements of glycemic control level in type 1 diabetes mellitus, especially in children. As iron deficiency anemia is a prevalent finding in children with diabetes, it may affect HbA1c levels in those children.
 Aim of the work:  To determine the effects of iron deficiency anemia on hemoglobin A1c in type 1 diabetes mellitus
Patients and methods:This was cross-sectional analytic study was done on 80 children with diabetes with type 1DM receiving insulin therapy; the patients divided into two groups, 21 diabetic children with iron deficiency anemia and 59 diabetic children with iron sufficient state, attending to the pediatric department of Al-Azher University Hospital in Damietta from February 2019 to September 2019. All children included were subjected to complete medical history, general examination, systemic examination, and laboratory investigations; [Complete blood count [CBC], HbA1c, Serum Iron, Serum Ferritin, Total Iron Binding Capacity, Fasting blood glucose, Post Prandial blood glucose, and ESR].
Results:In our study, we divided all patients [80 diabetic children] regarding glycemic control according to HbA1c value into three levels, the first level was optimal glycemic control level [HbA1c< 7.6%], the second level was suboptimal glycemic control [HbA1c 7.6 – 9.0%] and the third level was poor glycemic control level [HbA1c> 9.0%], there was a statically highly significant increase in HbA1c value of the iron-deficient diabetic group in compared to iron sufficient diabetic group at all levels of glycemic control.
Conclusion: Iron deficiency anemia seems to increase HbA1c value in diabetic children Type 1, at the same degree of glycemia.

DOI

10.21608/ijma.2020.46734.1193

Keywords

Hemoglobin A1c (HbA1c), iron deficiency anemia, Type-1 Diabetes Mellitus (T1DM)

Authors

First Name

Fatma

Last Name

El Nezely

MiddleName

Mustafa

Affiliation

Department of pediatrics and Neonatology Al-Azhar University-Faculty of medicine, Damietta, Egypt

Email

fatmaelnezely64@gmail.com

City

-

Orcid

-

First Name

Hussien

Last Name

Abd Elmaksoud

MiddleName

Metwally

Affiliation

Department of pediatrics and Neonatology Al-Azhar University-Faculty of medicine, Damietta, Egypt.

Email

dr.hussien19193@yahoo.com

City

-

Orcid

-

First Name

Magdy

Last Name

El Ghanam

MiddleName

Zaki

Affiliation

Department of Clinical Pathology, Al-Azhar University-Faculty of medicine, Damietta, Egypt

Email

magdy_elghannam2017@gmail.com

City

-

Orcid

-

Volume

3

Article Issue

1

Related Issue

21557

Issue Date

2021-01-01

Receive Date

2020-10-17

Publish Date

2021-01-01

Page Start

1,075

Page End

1,082

Print ISSN

2636-4174

Online ISSN

2682-3780

Article File

IJMA_Volume 3_Issue 1_Pages 1075-1082.pdf

PDF . 1.6MB

Link

https://ijma.journals.ekb.eg/article_124226.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=124226

Order

24

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

Relation between Iron Status and Hemoglobin A1c in Children with Type-1 Diabetes Mellitus

Details

Type

Article

Created At

22 Jan 2023