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120305

Assessment of Anti-Streptolysin-O Titre in Healthy School-Age Children in Alexandria Governorate

Article

Last updated: 04 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Pediatrics

Abstract

Background: Serology of streptococcal [GAS] group-A is used for post-streptococcal disease diagnoses, such as acute rheumatic fever, and occasionally for streptococcal pharyngitis diagnoses. Streptococcal titers vary according to a number of factors, including age and population. In developing countries, where GAS-induced impetigo is rare, the titers in healthy people are low in early childhood, peak in children aged 6 to 15, decrease in late adolescence and early adulthood, and then flatten off afterwards.
Aim of the work: To assess Anti streptolysin-O titre in healthy school age children in Alexandria governorate. 
Patients and Methods: A prospective study had been performed in Alexandria Governorate and the collected sample were tested in clinical pathology Lab [Al-Azhar University Hospital, Damietta]. A total of 3000 [1540 Males, 1460 Females] serum samples had been collected from children aged 6-15 years, had been tested for Anti-streptolysin O titer [ASO] by latex.
Results: ASO from 100-200 was higher with 1281 [42.7%] followed by
Conclusions: We concluded that upper limit of normal [ULN] ASOT is quite high in normal Egyptian children, reaching up to 850.0 IU / ml. Mapping of upper normal levels and associated factors with increased levels could provide a clue for future planning to prevent streptococcal infection and its associated complications.

DOI

10.21608/ijma.2020.42462.1163

Keywords

Group-A Streptococci [GAS], Anti-streptolysin O [ASO], Upper limit of normal, children, Alexandria-Governorate

Authors

First Name

Aziza

Last Name

Abdou

MiddleName

Abdelaziz

Affiliation

Department of Pediatrics, Damietta Faculty of medicine, Al-Azhar University, Egypt

Email

azizaabdelaziz2905@gmail.com

City

-

Orcid

-

First Name

Mohamed

Last Name

Zannoun

MiddleName

Abdel Salam

Affiliation

Department of Pediatrics, Damietta Faculty of medicine, Al-Azhar University, Egypt

Email

m-zannoun@yahoo.com

City

-

Orcid

-

First Name

Magdy

Last Name

El Ghanam

MiddleName

Zaki

Affiliation

Department of Clinical Pathology, Damietta Faculty of medicine, Al-Azhar University, Egypt

Email

magdy_elghannam2017@gmail.com

City

-

Orcid

-

Volume

3

Article Issue

1

Related Issue

21557

Issue Date

2021-01-01

Receive Date

2020-09-10

Publish Date

2021-01-01

Page Start

995

Page End

1,000

Print ISSN

2636-4174

Online ISSN

2682-3780

Article File

IJMA_Volume 3_Issue 1_Pages 995-1000.pdf

PDF . 949.3kB

Link

https://ijma.journals.ekb.eg/article_120305.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=120305

Order

13

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

Assessment of Anti-Streptolysin-O Titre in Healthy School-Age Children in Alexandria Governorate

Details

Type

Article

Created At

22 Jan 2023