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124697

Toxocariasis; A Neglected Tropical Disease, Association With Asthma, Chronic Urticaria and Unexplained Neurologic Manifestations Among Children

Article

Last updated: 24 Dec 2024

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Subjects

-

Tags

Pediatrics

Abstract

Background: The link between parasitic infestation and allergic diseases or unexplained neurologic manifestations was hypothesized, especially in children. However, the debate continues regarding this link.
Aim of the work: To determine the seroprevalence of toxocariasis in children with different allergic diseases [bronchial asthma and skin allergy], besides the unexplained neurological manifestations [epilepsy and focal neurologic deficits] in children.
Patients and methods: Children with bronchial asthma [40 children], skin allergy [40 children], and unexplained neurological manifestations [epilepsy and focal neurologic deficits], [40 children] were included. All underwent a full history taking, clinical examination, lab investigations, and seropositivity determination for Toxocara canis.
Results:Eosinophilia was reported in 22.5%, 30.0%, and 17.5% of asthma, skin, and unexplained neurological manifestations groups, respectively. In patients with asthma, the prevalence of toxocariasis was 15.0%; in skin disease, it was 7.5%, and in unexplained neurological manifestations, it was 12.5%. There was no significant difference between positive and negative toxocariasis regarding patient demographics. But there was a significant increase in contact with pets, chronic urticaria, lymph nodes involvement, and eosinophilia in positive when compared to negative groups.
Conclusion: The association between Toxocara canis infection and allergic diseases such as bronchial asthma, chronic urticaria, and unexplained neurological manifestations [epilepsy and focal neurologic deficits] was confirmed in the present work. The contact with dogs and cats [pets] was the major determinant risk factor explaining such association. Prospective cohort studies were warranted to examine the cause-effect relationship.

DOI

10.21608/ijma.2020.46359.1192

Keywords

bronchial asthma, children, Toxocariasis, Epilepsy, Chronic urticaria

Authors

First Name

Khaled Aly

Last Name

Temsah

MiddleName

-

Affiliation

Department of Parasitology, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

drkhaled2008@yahoo.com

City

Gharbia

Orcid

-

First Name

Mostafa Elshahat

Last Name

Mostafa

MiddleName

-

Affiliation

Department of Parasitology, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

mostafa.elshahat926@yahoo.com

City

New damietta

Orcid

-

First Name

Hany Abdul Hady

Last Name

El-Khaleegy

MiddleName

-

Affiliation

Pediatrics Department, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

hanykhaleegy@domazhermedicine.edu.eg

City

New damietta

Orcid

-

First Name

Atef Wahdan

Last Name

El Rifai

MiddleName

-

Affiliation

Department of Chest Disease, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

atefchest@gmail.com

City

Mansoura

Orcid

-

First Name

Mona

Last Name

Abd Raboo

MiddleName

-

Affiliation

Department of Parasitology, Faculty of Medicine for Girls, Al-Azhar University, Egypt.

Email

mona.rabo@yahoo.com

City

Cairo

Orcid

-

First Name

Sherief M.

Last Name

Al shazly

MiddleName

-

Affiliation

Department of Neurology, Damietta Faculty of Medicine, Al-Azhar University, Egypt.

Email

sheriefshazly15@gmail.com

City

new damietta

Orcid

-

Volume

3

Article Issue

1

Related Issue

21557

Issue Date

2021-01-01

Receive Date

2020-10-15

Publish Date

2021-01-01

Page Start

922

Page End

929

Print ISSN

2636-4174

Online ISSN

2682-3780

Article File

IJMA_Volume 3_Issue 1_Pages 922-929.pdf

PDF . 1.0MB

Link

https://ijma.journals.ekb.eg/article_124697.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=124697

Order

4

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

Toxocariasis; A Neglected Tropical Disease, Association With Asthma, Chronic Urticaria and Unexplained Neurologic Manifestations Among Children

Details

Type

Article

Created At

22 Jan 2023