Subjects
-Abstract
Background: Hyperuricemiais a common biochemical disturbance in which serum concentration of uric acid exceeds the normal values which is 7.0 mg/dl in men and more than 6.0 mg/dl in women leading to deposition of monosodium urate [MSU] crystals in joints and soft tissues resulting in inner ear functions affection.
Aim of the work: To elaborate the effect of hyperuricemia on the peripheral hearing as well as peripheral vestibular functions.
Subjects and Methods: This study included 40 subjects with hyperuricemia and 40 healthy controls. Participants underwent serum uric acid assay, full history taking, basic audiological evaluation and vestibular evaluation.
Results: 37[92.5%] hyperuricemic subjects had normal peripheral hearing sensitivity, only 3[7.5%] had mild high frequencies sensori-neural hearing loss [SNHL] at 8 kHz. 31[77.5%] Hyperuricemic patients had normal peripheral vestibular functions, only 9[22.5%] subjects had BPPV; They also had higher serum uric acid [SUA] level. No correlation between duration of hyperuricemia and occurrence of BPPV.
Conclusions: The hyperuricemic subjects had a significant higher incidence of BPPV. Other investigations to detect early and subtle changes in cochlear function of hyperuricemic subjects were recommended.
DOI
10.21608/ijma.2020.38516.1153
Keywords
Audio-vestibular, Sensorineural hearing loss, Vertigo, Hyperuricemia, Uric acid
Authors
First Name
Mohamed Mahmoud
MiddleName
-Affiliation
Audiovestibular Unit, Department of Otorhinolaryngology, Damietta Faculty of Medicine, Al-Azhar University, Egypt
Email
mm.sobki@domazhermedicine.edu.eg
Orcid
-First Name
Gehan Abd-Al-Rahman
MiddleName
-Affiliation
Audiovestibular Unit, Depart of Otorhinolaryngology, Faculty of Medicine, Al-Azhar University, Egypt
Orcid
-MiddleName
-Affiliation
Audiovestibular Unit, Depart of Otorhinolaryngology, Faculty of Medicine, Al-Azhar University, Egypt
Email
mam.aduio@domazhermedicine.edu.eg
Orcid
-First Name
Ahmed Abd El Moez Ali
MiddleName
-Affiliation
Department of Clinical pathology, Faculty of Medicine-Al-Azhar University, Egypt
Email
a.moez@domazhermedicine.edu.eg
Orcid
-Link
https://ijma.journals.ekb.eg/article_117260.html
Detail API
https://ijma.journals.ekb.eg/service?article_code=117260
Publication Title
International Journal of Medical Arts
Publication Link
https://ijma.journals.ekb.eg/
MainTitle
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