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117260

Audio-Vestibular Findings in Patients with Hyperuricemia

Article

Last updated: 04 Jan 2025

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Subjects

-

Tags

Otorhinolaryngology

Abstract

Background: Hyperuricemiais a common biochemical disturbance in which serum concentration of uric acid exceeds the normal values which is 7.0 mg/dl in men and more than 6.0 mg/dl in women leading to deposition of monosodium urate [MSU] crystals in joints and soft tissues resulting in inner ear functions affection.
Aim of the work: To elaborate the effect of hyperuricemia on the peripheral hearing as well as peripheral vestibular functions.
Subjects and Methods: This study included 40 subjects with hyperuricemia and 40 healthy controls. Participants underwent serum uric acid assay, full history taking, basic audiological evaluation and vestibular evaluation.
Results: 37[92.5%] hyperuricemic subjects had normal peripheral hearing sensitivity, only 3[7.5%] had mild high frequencies sensori-neural hearing loss [SNHL] at 8 kHz. 31[77.5%] Hyperuricemic patients had normal peripheral vestibular functions, only 9[22.5%] subjects had BPPV; They also had higher serum uric acid [SUA] level. No correlation between duration of hyperuricemia and occurrence of BPPV.
Conclusions: The hyperuricemic subjects had a significant higher incidence of BPPV. Other investigations to detect early and subtle changes in cochlear function of hyperuricemic subjects were recommended.

DOI

10.21608/ijma.2020.38516.1153

Keywords

Audio-vestibular, Sensorineural hearing loss, Vertigo, Hyperuricemia, Uric acid

Authors

First Name

Mohamed Mahmoud

Last Name

Al-Sobki

MiddleName

-

Affiliation

Audiovestibular Unit, Department of Otorhinolaryngology, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

mm.sobki@domazhermedicine.edu.eg

City

Mansura

Orcid

-

First Name

Gehan Abd-Al-Rahman

Last Name

El-Zarea

MiddleName

-

Affiliation

Audiovestibular Unit, Depart of Otorhinolaryngology, Faculty of Medicine, Al-Azhar University, Egypt

Email

dinagege@yahoo.com

City

Cairo

Orcid

-

First Name

Ahmed Mohamed

Last Name

Ahmed Mahmoud

MiddleName

-

Affiliation

Audiovestibular Unit, Depart of Otorhinolaryngology, Faculty of Medicine, Al-Azhar University, Egypt

Email

mam.aduio@domazhermedicine.edu.eg

City

Cairo

Orcid

-

First Name

Ahmed Abd El Moez Ali

Last Name

Saad

MiddleName

-

Affiliation

Department of Clinical pathology, Faculty of Medicine-Al-Azhar University, Egypt

Email

a.moez@domazhermedicine.edu.eg

City

Cairo

Orcid

-

Volume

2

Article Issue

4

Related Issue

17986

Issue Date

2020-10-01

Receive Date

2020-08-08

Publish Date

2020-10-01

Page Start

866

Page End

872

Print ISSN

2636-4174

Online ISSN

2682-3780

Article File

IJMA_Volume 2_Issue 4_Pages 866-872.pdf

PDF . 2.2MB

Link

https://ijma.journals.ekb.eg/article_117260.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=117260

Order

27

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

Audio-Vestibular Findings in Patients with Hyperuricemia

Details

Type

Article

Created At

22 Jan 2023