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107606

Comparison between a Bare–Metal Stents and Drug Eluting Stents in patients undergoing Percutaneous Coronary Intervention.

Article

Last updated: 04 Jan 2025

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Tags

Internal Medicine

Abstract

Background: little researches have directly compared second-generation drug-eluting stents with each other or with bare-metal stents.
Aim of the work: To compare between outcomes after implantation of bare-metal stents [BMS] and two kinds of 2nd generation drug eluting stents [DES] [Zotarolimus-Eluting Stents [ZES], and A Everolimus-Eluting Stents [EES]] in patients undergoing percutaneous coronary intervention.
Patients and Methods: 160 Ischemic Heart Disease [IHD] patients undergoing PCI with 2nd generation DES implantation [80 ZES and 80 EES] were analyzed against 50 IHD patients undergoing PCI with BMS implantation. Each patients group received up to 6 [in BMS group] or 24 months [in ZES and EES groups] of clopidogrel therapy. The key efficacy endpoint was the 24 months major adverse cardiac event [MACE] [death, myocardial infarction, or target lesion revascularization], whereas stent thrombosis [ST] was the safety endpoint.
Results: The MACE rate was lowest in EES [19%; χ2= 7.661], highest in BMS [41.7%; χ2 =7.661], and intermediate in ZES [28.2%; χ2= 7.661] group with significant P Value =0.002.The 2-year incidence of ST in the EES group [1.3%] was similar to that in the ZES-S group [2.2%], whereas it was lower in contrast with BMS [7.5%] groups, with significant P value= 0.004].
Conclusion: DES have more efficacy and safety than BMS as EES have lowest MACE and ST rate while BMS have the highest rate and ZES have intermediate rate while the three stent groups have similar rate of mortality at 2 years follow up.

DOI

10.21608/ijma.2020.35338.1145

Keywords

Bare Metal, Zotarolimus, Eluting Stents, Major adverse cardiac events, In Stent Restenosis, Stent Thrombosis

Authors

First Name

Khaled

Last Name

Alsayed

MiddleName

Ramadan

Affiliation

Cardiology, faculty of medecin, Al azhar University, Assiut branch

Email

dr.khaledramadan85@gmail.com

City

Egypt, Kafrel shiekh, Biala

Orcid

-

Volume

2

Article Issue

4

Related Issue

17986

Issue Date

2020-10-01

Receive Date

2020-07-10

Publish Date

2020-10-01

Page Start

786

Page End

792

Print ISSN

2636-4174

Online ISSN

2682-3780

Article File

IJMA_Volume 2_Issue 4_Pages 786-792.pdf

PDF . 2.3MB

Link

https://ijma.journals.ekb.eg/article_107606.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=107606

Order

16

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

Comparison between a Bare–Metal Stents and Drug Eluting Stents in patients undergoing Percutaneous Coronary Intervention.

Details

Type

Article

Created At

22 Jan 2023