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105776

Serum 25-hydroxyvitamin D concentration in Children with Lower Respiratory Tract Infection

Article

Last updated: 24 Dec 2024

Subjects

-

Tags

Pediatrics

Abstract

Background: Vitamin D plays a critical role in the human body. Its deficiency had been proposed to play a role in lower respiratory tract infections [LRTIs], which responsible for 18% of deaths in young children.
Aim of the work: The purpose of this study was to assess vitamin D concentrations in children with lower respiratory tract infections.
Patients and Methods:After obtaining approval of the ethics committee, a prospective case control study was conducted in pediatric department, Damietta Faculty of Medicine, Al-Azhar University Hospital on children with lower respiratory tract infections and comparing 25-hydroxyvitamin D level between them and normal matched control from December 2018 to September 2019 include 140 children, Group A: 70 cases children had lower respiratory tract infections [LRTIs] either isolated pneumonia or associated with sepsis. Group B: matched with 70 healthy subjects.
Results: There was significant reduction of vitamin D among study group children when compared to control group [13.68±5.50 s 40.64±4.76 ng/dl respectively]. There was no significant association between type of infection and vitamin D levels. However, all children with bronchitis had sufficient vitamin D levels. There were vitamin D-deficiency in 64.3% while No one was deficient vitamin D among control group.
Conclusion: Children with acute lower respiratory tract infection had significant reduction in vitamin D levels. The reduction had no significant association with the type of infection.

DOI

10.21608/ijma.2020.21996.1074

Keywords

25-Hydroxyvitamin D, Lower Respiratory Tract Infection, pneumonia, bronchiolitis, bronchitis

Authors

First Name

Asmaa Salah

Last Name

Barania

MiddleName

-

Affiliation

Department of Pediatrics, Damanhour Teaching Hospital, Ministry of Health, Egypt

Email

asmaabarania2@gmail.com

City

-

Orcid

-

First Name

Elbakry Mohammed

Last Name

Tharwat Elbakry

MiddleName

-

Affiliation

Department of Pediatrics, Damietta Faculty of Medicine Al-Azhar University, Egypt

Email

drbakry1@gmail.com

City

-

Orcid

-

First Name

Hany Abdel-Hady

Last Name

El-khaleegy

MiddleName

-

Affiliation

Department of Pediatrics, Damietta Faculty of Medicine Al-Azhar University, Egypt

Email

hanykhaleegy@yahoo.com

City

-

Orcid

-

First Name

Sabah

Last Name

Abdel-Raheem

MiddleName

Ibrahim

Affiliation

Department of Clinical Pathology, Damietta Faculty of Medicine Al-Azhar University, Egypt

Email

drsabahibrahim@yahoo.com

City

Damietta

Orcid

-

Volume

2

Article Issue

4

Related Issue

17986

Issue Date

2020-10-01

Receive Date

2020-01-05

Publish Date

2020-10-01

Page Start

757

Page End

762

Print ISSN

2636-4174

Online ISSN

2682-3780

Link

https://ijma.journals.ekb.eg/article_105776.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=105776

Order

12

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

Serum 25-hydroxyvitamin D concentration in Children with Lower Respiratory Tract Infection

Details

Type

Article

Created At

22 Jan 2023