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104413

Prevalence and Manifestation of Ototoxic Medications Among the Adult Attendees of The Audiovestibular unit at Al-Zahraa University Hospital, Cairo, Egypt

Article

Last updated: 22 Jan 2023

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Subjects

-

Tags

Otorhinolaryngology

Abstract

Background: Hearing loss is considered to be one of the most common factors of moderate to severe disability specially in the developing countries. Ototoxicity is inner ear damage due to usage of chemical substances, which can lead to either reversable or permanent hearing loss and/or vestibular loss. Ototoxic hearing impairment can impact the quality of life by many ways; therefore, we should be very careful when it comes to choose drug therapy to minimize the risk. 
Aim of the work:To identify the commonly implicated ototoxic medications among the adult Egyptian population and to study its presenting features.
Patients and Methods: This is a retrospective study, that involved review for the medical notes of all adult patients, who attended the Audio-Vestibular Unit with otological problems between January 2014 and December 2018. A total of 1110 medical folders were reviewed, and data were manually extracted.
Results: The prevalence of ototoxic medication among the adult attendees was 26.6%. The most common manifestation was hearing impairment, as it was reported in 83.2% of the cases. Tinnitus came second by 70% followed by vertigo in 31%. Aspirin was the most common drug used [44.7%] of the patients, followed by aminoglycoside in 15% of our study sample, then the non-steroidal anti-inflammatory drugs (NSAIDS) in 14.3%.
Conclusion: Audiometric screening is critical to capture the true prevalence of hearing loss. Baseline audiometric and vestibular function test should be performed before prescribing any ototoxic medication especially in patients with other associated risk factors

DOI

10.21608/ijma.2020.33846.1140

Keywords

Ototoxicity, Hearing Impairment, Tinnitus, Vertigo, Hearing Screening

Authors

First Name

Iman

Last Name

Eladawy

MiddleName

Ibrahim Mohamed

Affiliation

Department of Otorhinolaryngology, Audiovestibular Unit, Faculty of Medicine for Girls, Al-Azhar University, Egypt

Email

loay_sameh@yahoo.com

City

Cairo

Orcid

0000-0003-1108-1013

First Name

Amal

Last Name

Ahmed

MiddleName

Abdel Majid

Affiliation

Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine for Girls, Al-Azhar University, Egypt

Email

amal.mohamed53@yahoo.com

City

cairo

Orcid

-

First Name

Samia

Last Name

Barghash

MiddleName

-

Affiliation

Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine for Girls, Al-Azhar University, Egypt

Email

samiasolom@yahoo.com

City

-

Orcid

-

First Name

Hanaa

Last Name

Abu Elhassan

MiddleName

-

Affiliation

Department of Community Medicine, Faculty of Medicine for Girls, Al-Azhar University, Egypt

Email

hanaaabouelyazid@azhar.edu.eg

City

-

Orcid

-

Volume

2

Article Issue

4

Related Issue

17986

Issue Date

2020-10-01

Receive Date

2020-06-25

Publish Date

2020-10-01

Page Start

722

Page End

729

Print ISSN

2636-4174

Online ISSN

2682-3780

Article File

IJMA_Volume 2_Issue 4_Pages 722-729.pdf

PDF . 2.3MB

Link

https://ijma.journals.ekb.eg/article_104413.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=104413

Order

7

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023