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Effect of Sublingual Misoprostol Prior to Insertion of Intrauterine Device in Women with no Previous Vaginal Delivery

Article

Last updated: 04 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Gynecology and Obstetrics

Abstract

Background: The intrauterine device [IUD] is a safe and effective method of contraception, fear of pain during insertion discourages some providers to recommend IUDs to women with no previous vaginal delivery. 
Aim of the work:The aim of the study is to evaluate sublingual misoprostol 200µg on the cervix one hour before IUD insertion; to facilitate IUD insertion in women with tight cervix or in whom did not deliver vaginally.
Patients and Methods:The study was a double blinded randomized controlled trial, compared sublingual 200µg misoprostol with placebo. The study included 260 cases attended the Gynecology Clinic [Al-Azhar University Hospital] from December 2018 to November 2019. All females signed an informed written consent, and then have been randomly divided into 2 groups using a closed envelope technique. Every female had been asked to take the drug sublingually then return after one hour to insert her IUD. Group A included 130 females who used sublingual misoprostol 200µg [Misotac] and group B included 130 females who took a placebo one hour before IUD insertion [Control group].
Results: IUD and uterine sound insertion was unsuccessful in 8.5% of group A versus 13.8% in group B while it was successful in 91.5% of group A versus 86.2% in Group B. Among the successful cases, 88[73.9] were easy in group A versus 77[68.8] in group B. On the other hand, 31[26.1%] and 35[31.2%] were difficult in group A and B respectively. With no significant difference between both groups either in IUD or uterine sound insertion successful or easiness rate [p=0.17 & 0.38 respectively]
Conclusion: Using of misoprostol to facilitate IUD insertion in women with tight cervix, has no role in pain reduction or increase the ease of IUD insertion, although results with misoprostol are superior to placebo, but the different did not reach statistical significance

DOI

10.21608/ijma.2020.22013.1075

Keywords

misoprostol, intrauterine, device

Authors

First Name

Zeinab

Last Name

Elgharbawy

MiddleName

Mohamed

Affiliation

Department of Obstetrics and Gynecology, Port Fouad General Hospital, Ministry of Health and Populations, Egypt

Email

zeinabmohamedbody@gmail.com

City

Port Saied

Orcid

-

First Name

Abd Elraouf

Last Name

Oun

MiddleName

Mohamed

Affiliation

Department of Obstetrics and Gynecology, Damietta Faculty of Medicine, Al-Azhar University, Egypt.

Email

raoufoun2016@domazhermedicine.edu.eg

City

Damietta

Orcid

-

First Name

Waleed

Last Name

Ayad

MiddleName

Ahmed

Affiliation

Department of Obstetrics and Gynecology, Dameitta Faculty of Medicine, Al-Azhar University, Egypt.

Email

waled.ayad@domazhermedicine.edu.eg

City

Damietta

Orcid

-

Volume

2

Article Issue

3

Related Issue

16043

Issue Date

2020-07-01

Receive Date

2020-01-06

Publish Date

2020-07-01

Page Start

668

Page End

673

Print ISSN

2636-4174

Online ISSN

2682-3780

Article File

IJMA_Volume 2_Issue 3_Pages 668-673.pdf

PDF . 251.4kB

Link

https://ijma.journals.ekb.eg/article_85217.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=85217

Order

27

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

Effect of Sublingual Misoprostol Prior to Insertion of Intrauterine Device in Women with no Previous Vaginal Delivery

Details

Type

Article

Created At

22 Jan 2023