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91606

Assessment of Anti-Streptolysin O Titre in Healthy School Age Children in El Behira Governorate

Article

Last updated: 04 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Pediatrics

Abstract

Background: Group-A streptococcal serology is used for post-streptococcal disease diagnoses, such as acute rheumatic fever, and occasionally for diagnosis of streptococcal pharyngitis. The prevalence of rheumatic fever in school children aged 6 to 15 years ranges between 0.2 to 0.75 per 1000 children per year. The prevalence of rheumatic heart disease in 1000 children ranges from 1 to 5.4. 
Aim of the work: To determine upper limit of the normal range of Antistreptolysin O titre in healthy school children, aged 6-15 years old in El Behira governorate.
Patients and Methods:A cross-sectional study had been performed in EL Behira Governorate and the collected sample were tested in clinical pathology Lab [Al-Azhar University Hospital, Damietta]. A total of 3000 [1609 Males, 1391 Females] serum samples had been collected from children aged 6-15 years, had been tested for Anti-streptolysin O titer [ASO] by turbidimetry.
Results: Normal value for the ASO titer rose sharply during early childhood and then declined gradually with age. The estimated titer that was 80% of the upper limit or normal at age 10 years was 287 IU/ml for ASO.
Conclusion: This study provides the upper limit of normal value for ASO titre of school children. The "more than 400" rating should instruct clinicians in the treatment of post-streptococcal diseases in patients and provide valuable longitudinal evidence for potential intervention trials against streptococcal diseases in group A. 

DOI

10.21608/ijma.2020.23002.1089

Keywords

Group A Streptococci, Anti-streptolysin O, Upper limit of normal, children, El Behira

Authors

First Name

Mona

Last Name

Kordy

MiddleName

-

Affiliation

Department of Pediatrics, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

monamoustafa454@gmail.com

City

-

Orcid

-

First Name

Mohamed

Last Name

Zannoun

MiddleName

Abdel Salam

Affiliation

Department of Pediatrics, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

m_zannoun@yahoo.com

City

-

Orcid

-

First Name

Magdy

Last Name

El Ghanam

MiddleName

Zaki

Affiliation

Department of Clinical Pathology, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

magdy_elghannam2017@gmail.com

City

-

Orcid

-

Volume

2

Article Issue

3

Related Issue

16043

Issue Date

2020-07-01

Receive Date

2020-01-25

Publish Date

2020-07-01

Page Start

625

Page End

630

Print ISSN

2636-4174

Online ISSN

2682-3780

Article File

IJMA_Volume 2_Issue 3_Pages 625-630.pdf

PDF . 286.3kB

Link

https://ijma.journals.ekb.eg/article_91606.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=91606

Order

20

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

Assessment of Anti-Streptolysin O Titre in Healthy School Age Children in El Behira Governorate

Details

Type

Article

Created At

22 Jan 2023