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104865

Effect of Vitamin-D Supplementation on Recurrence of Acute Otitis Media in Pre-School Children

Article

Last updated: 22 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

Otorhinolaryngology

Abstract

Background: Acute Otitis media (AOM) and its recurrence is a prevalent health problem among pre-school children. Different strategies to prevent recurrent have been established with questionable efficacy. Vitamin D is suspected as a possible preventable risk factor. 
Aim of the work:To evaluate the effect of vitamin-D supplementation on recurrence rate of acute otitis media among Pre-school children.
Patients and Methods:60 pre-school children with a recurrent episode of acute otitis media [by history and otoscopic examination] were included. After diagnosis, all children received standard treatment and after recovery, serum levels of vitamin-D were estimated; those with reduced vitamin D had been included, then divided into: Study group (30 children, received oral vitamin-D supplementation for 4 months; and Control group (30 children; received placebo). New attacks of AOM had been document during the regular visits for the six months. Vitamin D had been re-estimated after 6 months.
Results: Both groups were comparable regarding studied variables at the start. Upper respiratory tract infection and ear discharge significantly decreased; vitamin D significantly increased among study group at 6 months. Recurrent AOM after 6 months, had been significantly reduced among study vs control group (1.43±0.62 vs 3.46±0.62 respectively). Also, vitamin-D significantly increased at the end in study vs control group (21.76±5.95 vs 14.53±4.73 ng/ml respectively). The mean percentage of increase of vitamin-D in study group was 135.98% compared to 33.91%. In control group.
Conclusion: Vitamin D supplementation to children with a history of rAOM plays a significant role in reduction of attack frequency.

DOI

10.21608/ijma.2020.34138.1141

Keywords

Vitamin-D, Recurrent otitis media, Upper respiratory infection, pre-school, children

Authors

First Name

Osama

Last Name

Refaat

MiddleName

Mohamed

Affiliation

Department of Otorhinolaryngology, Faculty of Medicine, Al-Azhar university, Egypt

Email

osamarefaat78@gmail.com

City

Cairo

Orcid

0000-0001-5752-097X

First Name

El Bakry

Last Name

Tharwat

MiddleName

Mohamed

Affiliation

Department of Pediatrics, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

drbakry1@domazhermedicine.edu.eg

City

Damietta

Orcid

-

First Name

Ahmed

Last Name

El-Gamal

MiddleName

Mohamed

Affiliation

Department of Clinical Pathology, Faculty of Medicine, Al-Azhar University, Egypt

Email

dr_ahmed5834777@yahoo.com

City

Cairo

Orcid

-

Volume

2

Article Issue

3

Related Issue

16043

Issue Date

2020-07-01

Receive Date

2020-06-30

Publish Date

2020-07-01

Page Start

604

Page End

610

Print ISSN

2636-4174

Online ISSN

2682-3780

Article File

IJMA_Volume 2_Issue 3_Pages 604-610.pdf

PDF . 292.9kB

Link

https://ijma.journals.ekb.eg/article_104865.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=104865

Order

17

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023