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82669

Inhaled Salbutamol for the Treatment of Transient Tachypnea of the Newborn

Article

Last updated: 22 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

Pediatrics

Abstract

Background: Transient tachypnea of the newborn [TTN] is a common physiologic lung disorder. Stimulation of β-adrenergic receptors could alleviate the condition.
Aim of the work: The study was undertaken to assess the efficacy and safety of inhaled salbutamol in reduction of TTN, oxygen treatment and hospitalization. 
Patients and Methods:This clinical study included 150 [50 control group, 50 single dose of salbutamol and 50 double-doses of salbutamol] infants between 35th-39th week's gestation. Inhaled salbutamol was given and comparison between the three groups was carried out.
Results: Treatable and control groups were comparable as regard neonatal and maternal characteristics. Heart rate was significantly increased in group B when compared to control group half and one hour after treatment. In addition, respiratory rate was significantly increase in group B when compared to group A at half hour after treatment and continued till 8 hours after treatment. The TTN score after treatment was significantly lower in group B when compared to group A at one hour after nebulized salbutamol and continued till 8 hours. Furthermore, time before initiation of feeding was significantly reduced in group B when compared to group A [26.72[±3.68] vs [39.66[±4.7] and also there was significant reduction of hospitalization days in group B when compared to group A [3.78 [±1.25] vs [7.36[±1.28].
Conclusion: Inhalational salbutamol reduced duration of supplemental oxygen therapy, the duration of hospitalization and time before initiation of feeding, and no adverse effects were reported. Thus, inhaled salbutamol seems to be effective and safe in TTN. 

DOI

10.21608/ijma.2020.21436.1064

Keywords

Neonate, Salbutamol, Transient, Tachypnea, Nebulized

Authors

First Name

Ahmed

Last Name

Salama

MiddleName

Abdelaty

Affiliation

Department of Pediatrics, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

drahmedsalama@yahoo.com

City

Sharqia

Orcid

-

First Name

Lotfy

Last Name

El-Seheimy

MiddleName

Abdel-Fattah

Affiliation

Department of Pediatrics, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

lotfi.alsehemy@domazhermedicine.eduae.eg

City

New Damietta

Orcid

-

First Name

Mohamed

Last Name

Elsamanoudy

MiddleName

Ibrahim

Affiliation

Department of Pediatrics, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

mohamed_elsamanody@yahoo.com

City

Tanta

Orcid

27801011202238

Volume

2

Article Issue

2

Related Issue

13522

Issue Date

2020-04-01

Receive Date

2019-12-29

Publish Date

2020-04-01

Page Start

457

Page End

461

Print ISSN

2636-4174

Online ISSN

2682-3780

Article File

IJMA_Volume 2_Issue 2_Pages 457-461.pdf

PDF . 277.1kB

Link

https://ijma.journals.ekb.eg/article_82669.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=82669

Order

18

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023