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Maternal Plasma Lipid Concentration in Third Trimester of Women with Preeclampsia and Normotensive Pregnancy

Article

Last updated: 22 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

Gynecology and Obstetrics

Abstract

Background: Preeclampsia is one of complications of pregnancy. It is responsible for morbidity for mother and fetus. Preeclampsia is a pregnancy multisystem disorder. Abnormal lipid profile has an effect on endothelial dysfunction. The association of serum lipid profile with preeclampsia is suggested to reflect new diagnostic tools. Pregnancy dyslipidemia is associated with an increased risk of preeclampsia. Compared to healthy pregnancy, women with preeclampsia have an abnormal lipid profile. 
Aim of the work: The aim of this work is comparison between normotensive women and preeclamptic women by serum lipid profile at third trimester.
Patients and Methods: The present study conducted on 70 pregnant women in the Department of Obstetrics and Gynecology, at Al-Azhar University hospital [Damietta], which was conducted during 2019 [from April to December]. A study comprised 35 normotensive pregnant women as controls and 35 preeclampsia cases. The blood samples were analyzed for serum triglycerides [TGs], total cholesterol [TC], high-density lipoprotein-cholesterol [HDL-C], low-density Lipoprotein-Cholesterol [LDL-C], very low-density Lipoprotein-Cholesterol [VLDL-C], Apo lipoprotein- A1 [Apo-A1] and Apo lipoprotein- B[Apo-B].
Results: There was significant difference between group A and B as regard Apo B/ Apo A1, cholesterol, TGS, LDL and VLDL. They are higher in group B.
Conclusion: In the third trimester of pregnancy, preeclamptic women have altered levels of serum lipid profile. The most significant test is Apo B/A1 ratio with accuracy [72.7%].

DOI

10.21608/ijma.2020.23839.1101

Keywords

preeclampsia, lipids, Apolipoprotein, Cholesterol, triglycerides

Authors

First Name

Ghada

Last Name

Mohammed

MiddleName

Khalil

Affiliation

Department of Obstetrics and Gynecology, Nabaruh General Hospital, Ministry of Health, Egypt.

Email

ghadakhalil2018@gmail.com

City

Mansoura

Orcid

-

First Name

Waleed

Last Name

Ayad

MiddleName

Ahmed

Affiliation

Department of Obstetrics and Gynecology, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

waled.ayad@domazhermedicine.edu.eg

City

Damietta

Orcid

-

First Name

Usama

Last Name

El-Gazzar

MiddleName

Bahgat

Affiliation

Department of Medical Biochemistry, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

usamagaz@yahoo.com

City

EL-manzala

Orcid

-

First Name

Samia

Last Name

Eid

MiddleName

Mohamed

Affiliation

Department of Obstetrics and Gynecology, Damietta Faculty of Medicine, Al-Azhar University, Egypt

Email

samiamohamad11@gmail.com

City

Damietta

Orcid

-

Volume

2

Article Issue

2

Related Issue

13522

Issue Date

2020-04-01

Receive Date

2020-02-10

Publish Date

2020-04-01

Page Start

405

Page End

411

Print ISSN

2636-4174

Online ISSN

2682-3780

Article File

IJMA_Volume 2_Issue 2_Pages 405-411.pdf

PDF . 436.1kB

Link

https://ijma.journals.ekb.eg/article_78267.html

Detail API

https://ijma.journals.ekb.eg/service?article_code=78267

Order

11

Type

Original Article

Type Code

816

Publication Type

Journal

Publication Title

International Journal of Medical Arts

Publication Link

https://ijma.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023